617695-07-5Relevant academic research and scientific papers
Microwave-assisted parallel synthesis of benzofuran-2-carboxamide derivatives bearing anti-inflammatory, analgesic and antipyretic agents
Xie, Yong-Sheng,Kumar, Deepak,Bodduri, V.D. Vijaykumar,Tarani, P. Srivastava,Zhao, Bao-Xiang,Miao, Jun-Ying,Jang, Kiwan,Shin, Dong-Soo
supporting information, p. 2796 - 2800 (2014/05/06)
A series of benzofuran-2-carboxamides of biological and medicinal significance were synthesized by a microwave-assisted one-pot parallel approach via O-alkylation/Knoevenagel condensation. All the compounds were characterized and assayed for their in vivo anti-inflammatory, analgesic and antipyretic activities. The activity data of all compounds were listed and discussed in detail, among which some derivatives exhibited potent activities of particular interest.
