61775-19-7

Basic information

• Product Name: 5-O-Methylnaringenin
• Synonyms: 5-O-Methylnaringenin;(S)-7-Hydroxy-2-(4-hydroxyphenyl)-5-MethoxychroMan-4-one;7,4′-Dihydroxy-5-methoxyflavanone;Naringenin 5-O-methyl ether
• CAS NO: 61775-19-7
• Molecular Formula: C16H14O5
• Molecular Weight: 286.27936
• EINECS: 200-258-5
• Mol File: 61775-19-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 231-232 °C
• Boiling Point: 555.9°Cat760mmHg
• Flash Point: 212.4°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 5.76E-13mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: ?20°C
• PKA: 7.35±0.40(Predicted)
• CAS DataBase Reference: 5-O-Methylnaringenin(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-Methylnaringenin(61775-19-7)
• EPA Substance Registry System: 5-O-Methylnaringenin(61775-19-7)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 61775-19-7(Hazardous Substances Data)

Usage

General Description

5-O-Methylnaringenin is a chemical compound, specifically a flavanone, naturally found in select citrus fruits, barley, and hops. It is recognized for its potential health benefits, including antioxidant, anti-inflammatory, and anticancer effects. Its unique structure allows it to easily attach to cell membranes, potentially inhibiting the growth of harmful cells. The compound also stands out for its possible role in brewing, as its presence might affect the taste of beer due, in part, to its antioxidative qualities. However, while research on 5-O-Methylnaringenin indicates promising results, more extensive studies are needed to further understand its comprehensive properties and potential uses.

InChI:InChI=1/C16H14O5/c1-20-14-6-11(18)7-15-16(14)12(19)8-13(21-15)9-2-4-10(17)5-3-9/h2-7,13,17-18H,8H2,1H3/t13-/m0/s1

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 52077-36-8 4'-β-D-glucopyranosyloxy-4,2'-dihydroxy-6'-methoxy-trans-chalcone 

Downstream Products

• 70872-29-6 Isoxanthohumol 
• 108977-51-1 naringenin 5-methyl ether 7,4'-diacetate 

Relevant articles and documents

A chalcone glycoside from Clerodendron phlomidis

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Novel flavanone and chalcone glycosides from Clerondendron phlomidis (Verbenaceae)

Oven dried ground roots and flowers of Clerodendron phlomidis yield two flavonoidglycosides, ∞-L-Rhamnopyranosyl-(1→2)-∞-D-glucopyranosyl-7-O- naringin-4'-O-∞-D-glucopyranoside-5-methyl ether 1 and 4, 2', 4'-trihydroxy- 6'-methoxychalcone-4, 4'-∞-D-diglucoside 5.

Novel flavone and chalcone glycosides from clerodendron phlomidis (verbenaceae)

Photochemical investigation of oven dried ground roots and flowers of Clerodendron phlomidis lead to the isolation of two flavonoidglycosides, α-L-Rhamnopyranosyl-(1→2)-α-.D-Glucopyranosyl-7-0-naringin-4-0- α-D-glucopyranoside-5-methylether 1 and 4, 2′, 4′-trihydroxy-6′-methoxy chalcone-4,4′-α-D-diglucoside 5.Their structures have been established by spectroscopic studies . . .