61784-26-7Relevant academic research and scientific papers
Ionic hydrogenation of oxyallyl intermediates: The reductive nazarov cyclization
Giese, S?ren,West
, p. 10221 - 10228 (2007/10/03)
Cyclization of tri- and tetrasubstituted dienones 1 under Lewis acidic conditions in the presence of triethylsilane led to formation of either silyl enol ethers 6 or cyclopentanones 7 in good to excellent yields, depending on work-up conditions. The proposed mechanism involves initial Nazarov cyclization to give oxyallyl intermediates 5, which are intercepted via intermolecular transfer of hydride. The reactions proceeded cleanly with as little as 2 equiv. of silane and in most cases catalytic amounts of Lewis acid could be used. Trapping with Et3SiD occurs at the less substituted terminus in unsymmetrical cases. (C) 2000 Elsevier Science Ltd.
A significant effect of anion binding ureas on the product ratio in the palladium(II)-catalyzed hydrocarbonylation of alkenes
Scheele, Jan,Timmerman, Peter,Reinhoudt, David N.
, p. 2613 - 2614 (2007/10/03)
Hydrogen bonding of urea derivatives to the anionic ligands X of (dppp)PdX2 catalysts significantly increases the hydroacylation of cyclopentene relative to the hydroformylation, most probably due to a decreased coordination strength of the anionic ligands.
The reductive Nazarov cyclization
Giese, Soeren,West
, p. 8393 - 8396 (2007/10/03)
Tri- and tetrasubstituted 1,4-dien-3-ones 1 were treated with Lewis acid in the presence of triethylsilane, furnishing either silyl enol ethers 4 or cyclopentanones 5 in good yields, depending upon work-up conditions. This reaction is presumed to occur th
