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5-Fluoro-2',3'-O-isopropylidene-D-cytidine, also known as 2',3'-O-Isopropylidene-5-fluorocytidine (CAS# 61787-04-0), is a synthetic nucleoside analog with a unique chemical structure. It features a fluorine atom at the 5-position and an isopropylidene protecting group at the 2' and 3' positions of the cytidine molecule. 5-Fluoro-2',3'-O-isopropylidene-D-cytidine is known for its potential applications in various fields, particularly in organic synthesis.

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  • 61787-04-0 Structure
  • Basic information

    1. Product Name: 5-Fluoro-2',3'-O-isopropylidene-D-cytidine
    2. Synonyms: 5-Fluoro-2',3'-O-isopropylidene-D-cytidine;5-Fluoro-2',3'-O-isopropylidenecytidine
    3. CAS NO:61787-04-0
    4. Molecular Formula: C12H16FN3O5
    5. Molecular Weight: 301.27
    6. EINECS: N/A
    7. Product Categories: Bases & Related Reagents;Nucleotides
    8. Mol File: 61787-04-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 442.1±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.73±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 14.14±0.10(Predicted)
    10. CAS DataBase Reference: 5-Fluoro-2',3'-O-isopropylidene-D-cytidine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-Fluoro-2',3'-O-isopropylidene-D-cytidine(61787-04-0)
    12. EPA Substance Registry System: 5-Fluoro-2',3'-O-isopropylidene-D-cytidine(61787-04-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 61787-04-0(Hazardous Substances Data)

61787-04-0 Usage

Uses

Used in Organic Synthesis:
5-Fluoro-2',3'-O-isopropylidene-D-cytidine is used as a key intermediate in the synthesis of various biologically active compounds. Its unique structure allows for the development of novel nucleoside analogs with potential applications in medicinal chemistry and drug discovery.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Fluoro-2',3'-O-isopropylidene-D-cytidine is utilized as a building block for the synthesis of antiviral and anticancer drugs. Its ability to mimic natural nucleosides and incorporate into nucleic acids makes it a promising candidate for the development of new therapeutic agents.
Used in Research and Development:
5-Fluoro-2',3'-O-isopropylidene-D-cytidine is also employed as a research tool in academic and industrial laboratories. It aids scientists in understanding the mechanisms of nucleic acid synthesis, replication, and repair, as well as in the study of drug resistance and the development of targeted therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 61787-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,7,8 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 61787-04:
(7*6)+(6*1)+(5*7)+(4*8)+(3*7)+(2*0)+(1*4)=140
140 % 10 = 0
So 61787-04-0 is a valid CAS Registry Number.

61787-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2',3'-O-Isopropylidene-5-fluorocytidine

1.2 Other means of identification

Product number -
Other names 5-Fluoro-2',3'-O-isopropylidene-D-cytidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61787-04-0 SDS

61787-04-0Upstream product

61787-04-0Downstream Products

61787-04-0Relevant articles and documents

5'-Deoxy-5-fluoropyrimidine nucleosides

-

, (2008/06/13)

Novel 5'-deoxy-5-fluoropyrimidine nucleosides are potent anti-tumor agents. Preferred compounds are 5'-deoxy-5-fluorocytidine and 5'-deoxy-5-fluorouridine.

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