61798-26-3

Usage

Chemical structure

Heterocyclic amine derivative with an ethylenediamine core and a substituted phenylthioethyl group

Common uses

a. Organic synthesis
b. Pharmaceutical research

Bonding ability

Forms stable covalent bonds with various functional groups

Potential applications

a. Building block in the development of biologically active molecules
b. Building block in the development of pharmaceutical drugs

Safety concerns

a. Health risks if not properly managed
b. Environmental risks if not properly managed

Precaution

Handle with care to minimize exposure and potential hazards

Upstream product

• 23545-41-7 N-(2-bromo-ethyl)-ethylenediamine; dihydrobromide 
• 108-98-5 thiophenol 

Downstream Products

• 61797-83-9 Nonanoic acid (2-nonanoylamino-ethyl)-(2-phenylsulfanyl-ethyl)-amide 

Relevant academic research and scientific papers

Novel S-substituted aminoalkylamino ethanethiols as potential antidotes against sulfur mustard toxicity

Sulfur mustard (SM) is a highly toxic chemical warfare agent. A satisfactory treatment regimen is not yet available for this toxicant. In a search for an effective antidote against SM, a series of novel S-2(ω-aminoalkylamino)ethyl alkyl/aryl thioethers [H2N(CH 2)nNHCH2CH2SR], where R = alky, alicyclic, aryl, and heterocyclic substituents, have been designed and synthesized as candidate antidotes against SM toxicity. These compounds were screened for their protective efficacy through the oral route against dermally applied sulfur mustard in female mice measured on the basis of percent survival following percutaneous administration of SM. A number of compounds demonstrated significant protection.