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Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-N,2-dihydroxybenzenecarboxamide is used as an anti-cancer agent for its cytotoxic activity against various cancer cell lines. It has shown promise in targeting and inhibiting the growth of cancer cells, making it a valuable candidate for further research and development in oncology.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-Bromo-N,2-dihydroxybenzenecarboxamide serves as a key intermediate or reagent in the production of various organic compounds. Its unique structure and reactivity contribute to the synthesis of a range of chemical products.
Used in Corrosion Inhibition:
4-Bromo-N,2-dihydroxybenzenecarboxamide is used as a corrosion inhibitor due to its capacity to form a protective layer on metal surfaces. This property makes it a potential candidate for applications in industries where metal protection is crucial, such as in the automotive, aerospace, and construction sectors.
Further research is necessary to explore the full spectrum of applications and properties of 4-Bromo-N,2-dihydroxybenzenecarboxamide, ensuring its safe and effective use across different industries.

Upstream product

• 22717-56-2 4-bromo-2-Hydroxybenzoic Acid Methylester 
• 1666-28-0 4-bromosalicylic acid 

Downstream Products

• 65685-51-0 6-bromo-1,2-benzoxazol-3-ol 

Relevant academic research and scientific papers

BENZOISOXAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION

Compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.

Chromatography-free, Mitsunobu-triggered heterocyclizations of salicylhydroxamic acids to 3-hydroxybenzisoxazoles

The Mitsunobu reaction has become one of the most powerful tools to alkylate acidic pronucleophiles. A significant caveat of Mitsunobu chemistry, however, is that the reaction mixture is often plagued with purification problems owing to the phosphine oxide and hydrazine dicarboxylate by-products. In addition to the development of more readily separable Mitsunobu reagents, the product's physicochemical properties may be exploited to facilitate purification. In this regard, we present a swift and efficient preparation of 3-hydroxybenzisoxazoles by the Mitsunobu-triggered heterocyclizations of salicylhydroxamic acids, which can be isolated by an acid–base work-up. As expected, a range of functional groups was compatible with the chemistry.

FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS

Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.