61807-33-8Relevant academic research and scientific papers
Photocatalytic anion oxidation achieves direct aerobic difunctionalization of alkenes leading to β-thiocyanato alcohols
Zhang, Wei,Guo, Jun-Tao,Yu, Yue,Guan, Zhi,He, Yan-Hong
, p. 3038 - 3044 (2018/05/16)
A novel visible light-driven oxidative cascade reaction for the synthesis of β-thiocyanato alcohols via difunctionalization of alkenes is described for the first time. In this protocol inorganic ion thiocyanate was successfully converted into radical through photocatalysis by employing Rose Bengal as a photocatalyst to mediate the single-electron transfer. This hydroxylation process did not need extra reducing agent and the new C–S and C–O bonds could be constructed in one pot. Molecular oxygen not only was used as an excellent terminal oxidant, but also served as a green oxygen source, which is one of the most ideal processes to realize C–H bond oxidation functionalization. Moreover, the reaction also proceeded very well under irradiation of sunlight.
1,1-Diphenyl-2-methylsulfinyl ethanol: A model compound to study the reactivity towards CNBr of a photoadduct of methionine on CγH2
Sachon, Emmanuelle,Milcent, Thierry,Sagan, Sandrine,Convert, Odile,Chassaing, Gérard,Lavielle, Solange
, p. 7485 - 7489 (2007/10/03)
The photoadduct formed by photolysis of the [Bapa0, (pBzl)Phe5, Met(O2)11]SP/NK-1 complex localised within the T173MP175 domain of the NK-1 receptor cannot be cleaved by CNBr on the C-side of methionine; an unusual rearrangement of the intermediate sulfonium instead occurred. The reactivity of 1,1-diphenyl-2-methylsulfinyl ethanol 10 towards CNBr treatment and the stability of the 1,1-diphenyl oxirane 14 were analysed by NMR and mass spectrometry. 1,1-Diphenyl ethylene 13 can be formed from epoxide 14 even in slightly acidic conditions and during positive DCI/NH3 mass spectrometry analysis. Altogether, these results suggest that if a covalent linkage between the [Bapa0, (pBzl)Phe5, Met(O2)11] and the NK-1 receptor occurred on the CγH2 of methionine-174, CNBr treatment will lead to an epoxide/ketone and an ethylenic compound.
