618084-27-8

Usage

Chemical structure

A complex structure containing a dioxane ring, two carbonyl groups, a 3,5-dimethoxyphenylmethyl side group, and two methyl groups attached to the dioxane ring.

Dioxane ring

A six-membered cyclic ether with two oxygen atoms in the ring.

Carbonyl groups

Two carbonyl groups (C=O) are present in the 4 and 6 positions of the dioxane ring, making it a dione.

3,5-Dimethoxyphenylmethyl side group

A phenyl group (C6H5) with two methoxy groups (-OCH3) attached to the 3 and 5 positions, and a methyl group (-CH3) attached to the benzylic carbon.

Methyl groups

Two methyl groups (-CH3) are attached to the 2 position of the dioxane ring.

Potential applications

Organic synthesis and pharmaceutical research due to its unique structure and reactivity.

Further research

Additional research and testing are needed to determine its specific uses and potential benefits in various industries.

Molecular weight

Approximately 252.27 g/mol (calculated from the molecular formula)

Functional groups

Ether, carbonyl, phenyl, and methoxy groups are present in the molecule.

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 7311-34-4 3,5-dimethoxybenzaldehdye 

Downstream Products

• 618085-52-2 5-(3,5-dimethoxybenzyl)-2,2,5-trimethyl-1,3-dioxane-4,6-dione 
• 717-94-2 3-(3,5-dimethoxyphenyl)propionic acid 
• 61227-52-9 5,7-dimethoxy-2-methylindan-1-one 
• 880-87-5 5,7-dimethoxyindan-1-one 

Relevant academic research and scientific papers

Convenient Access to Polysubstituted 1-Indanones by Sc(OTf) 3-Catalyzed Intramolecular Friedel-Crafts Acylation of Benzyl Meldrum's Acid Derivatives

(Matrix presented) The intramolecular Friedel-Crafts acylation of benzyl Meldrum's acids is catalyzed by Sc(OTf)3 under mild reaction conditions. Several polysubstituted 1-indanones have been prepared.

For forming the functional polymer film of the coating liquid and functional polymer film forming method

Provided is a coating solution for forming a functional polymer film, said coating solution containing: at least one type of modifying compound selected from the group represented by formula A-D and having at least one Meldrum's acid structural site and a functional structural site which imparts functionality; and a polymer for modification or a monomer for the synthesis of said polymer for modification. Also provided is a functional polymer film obtained by firing a substrate coated using said coating. (In the formulae, the symbols are groups as defined in claim 1.)

Meldrum's acids as acylating agents in the catalytic intramolecular Friedel-Crafts reaction

(Chemical Equation Presented) The intramolecular Friedel-Crafts acylation of aromatics with Meldrum's acid derivatives catalyzed by metal trifluoromethanesulfonates is reported. Meldrum's acids are easily prepared, functionalized, handled, and purified. The synthesis of polysubstituted 1-indanones from benzyl Meldrum's acids was investigated thoroughly, and it was shown that a variety of catalysts were effective, while accommodating a diversity of functional groups under mild conditions. The scope, limitations, and functional group tolerance (terminal alkene and alkyne, ketal, dialkyl ether, dialkyl thioether, aryl methyl ether, aryl TIPS and TBDPS ethers, nitrile- and nitro-substituted aryls, alkyl and aryl halides) for a variety of 5-benzyl (enolizable Meldrum's acids) and 5-benzyl-5-substituted Meldrum's acids (quaternized Meldrum's acids), forming 1-indanones and 2-substituted-1- indanones, respectively, are delineated. This method was further applied to the synthesis of 1-tetralones, 1-benzosuberones, and the potent acetylcholinesterase inhibitor donepezil. Rate of cyclization as a function of ring size was established for various benzocyclic ketones via competition experiments: 1-tetralones form faster than both 1-indanones and 1-benzosuberones, and 1-benzosuberones cyclize faster than 1-indanones.