61837-66-9

Basic information

• Product Name: (+/-)-4'-HYDROXYNIRVANOL
• Synonyms: 5-ethyl-5-(4-hydroxyphenyl)-2,4-imidazolidinedione;5-ethyl-5-(4-hydroxyphenyl)-4-imidazolidinedione;rac-5-Ethyl-(5-hydroxyphenyl)hydantoin;rac-5-Ethyl-5-(4-hydroxyphenyl)-2,4-imidazolidinedione,rac-4-Hydroxynirvanol;(±)-5-Ethyl-5-(4-hydroxyphenyl)hydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)imidazolinidine-2,4-dione;rac-5-Ethyl-(5-Hydroxyphenyl)hydantoin Discontinued See H949220;1-Ethyl-1-(4-hydroxyphenyl)-3-(2-oxoethyl)urea
• CAS NO: 61837-66-9
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.22458
• Product Categories: Hydantoins & Derivatives;Metabolites & Impurities;Aromatics;Metabolites
• Mol File: 61837-66-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 260 °C
• Appearance: white/
• Density: 1.277g/cm³
• Refractive Index: 1.567
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: (+/-)-4'-HYDROXYNIRVANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-4'-HYDROXYNIRVANOL(61837-66-9)
• EPA Substance Registry System: (+/-)-4'-HYDROXYNIRVANOL(61837-66-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 2
• RTECS: NI9453716
• Hazardous Substances Data: 61837-66-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 61837-66-9 differently. You can refer to the following data:
1. A mephentoin metabolite
2. A mephytoin metabolite.

InChI:InChI=1/C11H12N2O3/c1-2-11(9(15)12-10(16)13-11)7-3-5-8(14)6-4-7/h3-6,14H,2H2,1H3,(H2,12,13,15,16)

Upstream product

• 506-87-6 ammonium carbonate 
• 70-70-2 4-hydroxypropiophenone 
• 151-50-8 potassium cyanide 

Downstream Products

• 61837-65-8 (+/-)-4'-Hydroxymephenytoin 
• 1173022-56-4 [2H₃]3-methyl-5-ethyl-5-(4-hydroxyphenyl)hydantoin 

Relevant articles and documents

Solvent effects on the absorption spectra of potentially pharmacologically active 5-alkyl-5-arylhydantoins: A structure-property relationship study

To obtain insight into the interactions of potential anticonvulsant drugs with their surrounding, two series of 5-methyl-5-aryl- and 5-ethyl-5- -arylhydantoins were synthesized and their absorption spectra were recorded in the region from 200 to 400 nm in a set of selected solvents. The effects of solvent dipolarity/polarizability and solvent-solute hydrogen bonding interactions on the absorption maxima shifts were analyzed by means of the linear solvation energy relationship (LSER) concept of Kamlet and Taft. The ratio of the contributions of specific and non-specific solvent-solute interactions were correlated with the corresponding absorption, distribution, metabolism, and excretion (ADME) properties of the studied compounds. The correlation equations were combined with different physicochemical parameters to generate new equations, which demonstrate the reasonable relationships between the solvent- solute interactions and the structure-activity parameters. Copyright (C)2013 SCS.

Hydantoin derivatives

New hydantoin derivatives, a process for the preparation thereof and pharmaceutical compositions containing the derivatives as active ingredients, particularly remedies for treatment of diseases caused by stress.