618385-01-6 Usage
Uses
Used in Cardiovascular Medicine:
Vorapaxar is used as an antagonist for the prevention of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease. It functions by inhibiting platelet aggregation, which helps to reduce the risk of further cardiovascular complications.
Used in Pharmaceutical Formulations:
Vorapaxar is used as an active pharmaceutical ingredient in the development of formulations aimed at reducing thrombotic cardiovascular events. These formulations are specifically designed to target PAR1, providing a selective and effective treatment option for patients at risk of such events.
references
[1]. chackalamannil s & xia, y. thrombin receptor (par-1) antagonists as novel antithrombotic agents. expert opinion on therapeutic patents, 2006.16:493-505.[2]. chackalamannil s, wang y, greenlee w j et al. 2008. discovery of a novel, orally active himbacine-based thrombin receptor antagonist (sch 530348) with potent antiplatelet activity. j med chem, 2008,51: 3061-3064.
Check Digit Verification of cas no
The CAS Registry Mumber 618385-01-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,8,3,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 618385-01:
(8*6)+(7*1)+(6*8)+(5*3)+(4*8)+(3*5)+(2*0)+(1*1)=166
166 % 10 = 6
So 618385-01-6 is a valid CAS Registry Number.
InChI:InChI=1/C29H33FN2O4/c1-3-35-29(34)32-23-10-11-24-20(14-23)15-26-27(17(2)36-28(26)33)25(24)12-9-22-8-7-19(16-31-22)18-5-4-6-21(30)13-18/h4-9,12-13,16-17,20,23-27H,3,10-11,14-15H2,1-2H3,(H,32,34)/b12-9+/t17-,20+,23-,24-,25+,26-,27+/m1/s1
