(1-(2-Chlorophenyl)-3-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)methanol, also known as TPA023, is a psychoactive drug that functions as a selective agonist at the GABA-A α2 and α3 subtype receptors. It is a derivative of the pyrazolopyridine class of drugs and has been studied for its potential therapeutic applications in treating anxiety and related disorders.
618441-96-6
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Basic information
- Product Name: (3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL
- Synonyms: (3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL;SALOR-INT L446513-1EA;(1-(2-CHLOROPHENYL)-3-(2,4-DICHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL
- CAS NO:618441-96-6
- Molecular Formula: C16H11Cl3N2O
- Molecular Weight: 353.63
- EINECS: N/A
- Product Categories: N/A
- Mol File: 618441-96-6.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL(CAS DataBase Reference)
- NIST Chemistry Reference: (3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL(618441-96-6)
- EPA Substance Registry System: (3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL(618441-96-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 618441-96-6(Hazardous Substances Data)
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618441-96-6 Usage
Uses
Used in Pharmaceutical Industry:TPA023 is used as a potential anxiolytic and sedative agent for the treatment of anxiety and other related disorders. It has demonstrated anxiolytic and sedative effects in preclinical studies, indicating its potential to alleviate symptoms associated with anxiety.
However, it is important to note that the clinical development of TPA023 has been limited due to concerns about potential side effects. Further research is required to determine its safety and efficacy in humans, which would be crucial for its application in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 618441-96-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,8,4,4 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.Calculate Digit Verification of CAS Registry Number 618441-96:
(8*6)+(7*1)+(6*8)+(5*4)+(4*4)+(3*1)+(2*9)+(1*6)=166
166 % 10 = 6
So 618441-96-6 is a valid CAS Registry Number.
618441-96-6Upstream product
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(3-(2,4-DICHLOROPHENYL)-1-(2-CHLOROPHENYL)-1H-PYRAZOL-4-YL)METHANOL
