618456-97-6Relevant articles and documents
Preparation and in vitro evaluation of GdDOTA-(BOM)4; a novel angiographic MRI contrast agent.
Hovland, Ragnar,Aasen, Arne J,Klaveness
, p. 1707 - 1710 (2007/10/03)
A novel Gd(III) complex, GdDOTA-(BOM)4, has been prepared by a simple three-step procedure. The complex showed high T1-relaxivity values in serum albumin solutions, blood and plasma, resulting from high affinity for serum albumin. The T1-relaxivity in plasma, 67.4 s-1 mM-1 (20 MHz, 37 degrees C), makes it a promising candidate for angiographic applications of MRI.