61853-41-6

Basic information

• Product Name: (3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione
• Synonyms: (3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione
• CAS NO: 61853-41-6
• Molecular Formula: C₁₂H₁₀O₄
• Molecular Weight: 218.2054
• Mol File: 61853-41-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 483.9°Cat760mmHg
• Flash Point: 221.5°C
• Appearance: /
• Density: 1.326g/cm³
• Vapor Pressure: 1.61E-09mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: (3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione(CAS DataBase Reference)
• NIST Chemistry Reference: (3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione(61853-41-6)
• EPA Substance Registry System: (3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione(61853-41-6)

Safety Data

• Hazardous Substances Data: 61853-41-6(Hazardous Substances Data)

Usage

General Description

(3Z)-3-(4-Methoxybenzylidene)-2,4(3H,5H)-furandione, also known as 4-Methoxybenzylidene-2,3-dihydro-3(2H)-furanone, is an organic compound with the molecular formula C12H10O4. It is a furanone derivative that exists as a yellow solid at room temperature. This chemical is commonly used in the field of organic synthesis and research due to its versatile reactivity and unique chemical properties. It is also used as a flavoring agent in food and beverages. The compound has potential applications in the pharmaceutical and agricultural industries, and research is ongoing to explore its potential uses in these areas.

InChI:InChI=1/C12H10O4/c1-15-9-4-2-8(3-5-9)6-10-11(13)7-16-12(10)14/h2-6H,7H2,1H3

Upstream product

• 108-30-5 succinic acid anhydride 
• 123-11-5 4-methoxy-benzaldehyde 
• 4971-56-6 tetrahydrofuran-2,4-dione 

Downstream Products

• 930765-12-1 3-(4-methoxybenzyl)tetrahydrofuran-2,4-dione 
• 918340-26-8 8,11-dihydro-11-(4-methoxyphenyl)benzo[f]furo[3,4-b]quinolin-10(7H)-one 

Relevant articles and documents

Synthesis of an Iridoid-Inspired Compound Collection and Discovery of Autophagy Inhibitors

Iridoids comprise a large group of monoterpenoid natural products displaying a diverse array of biological activities ranging from neurotrophic to anti-inflammatory and anti-tumorigenic properties. Therefore, the development of concise synthesis routes to compound collections inspired by the structural features of these natural products is of particular relevance for chemical biology and medicinal chemistry. Herein we describe a samarium diiodide-mediated synthesis of a small, focused iridoid-inspired compound collection. Characterization of these iridoid analogues in biological assays revealed novel small-molecule inhibitors of autophagy.

Tetronic acid in reaction with aromatic aldehydes and 2-naphthylamine. Investigation of fluorescent and nonlinear-optical characteristics of compounds obtained

By Knoevenagel condensation and by three-component condensation 3-arylmethylenetetrahydrofuran-2,4-diones and previously unknown 8,11-dihydro-11-arylbenzo[f]furo[3,4-b]quinolin-10(7H)-ones were respectively synthesized. The luminescent spectra and nonline