61854-73-7

Upstream product

• 141-82-2 malonic acid 
• 91-56-5 indole-2,3-dione 

Downstream Products

• 64230-47-3 (3-bromo-2-oxo-2,3-dihydro-indol-3-yl)-acetic acid 
• 205760-03-8 [3-(4-Methoxy-phenylamino)-2-oxo-2,3-dihydro-1H-indol-3-yl]-acetic acid 
• 205760-05-0 [3-(4-Bromo-phenylamino)-2-oxo-2,3-dihydro-1H-indol-3-yl]-acetic acid 
• 205760-04-9 [3-(4-Chloro-phenylamino)-2-oxo-2,3-dihydro-1H-indol-3-yl]-acetic acid 
• 205760-02-7 (2-Oxo-3-p-tolylamino-2,3-dihydro-1H-indol-3-yl)-acetic acid 
• 205760-01-6 (2-Oxo-3-phenylamino-2,3-dihydro-1H-indol-3-yl)-acetic acid 

Relevant academic research and scientific papers

Synthesis of some new spiro[indoline-3,2′-(1′,2′,3′,4′- tetrahydroquinoline)]-2,4′-dione derivatives

Indole-2,3-dione (1) was treated with malonic acid in a mixture of ethanol/pyridine to afford 3-(2-oxoindolinylidine)acetic acid (2), which then reacted with hydrobromic acid to yield 3-bromo-3-(2-oxoindole)acetic acid (3). Compound (3) reacted with aroma

A FACILE ROUTE FOR THE SYNTHESIS OF SOME NEW SPIRO-2,1'-DIONE DERIVATIVES

Indole-2,3-dione (1) was treated with malonic acid in a mixture of ethanol/pyridine to afford 1-acetic acid (5).Compounds (5) reacted with arenes in the presence of aluminium chloride as catalyst to yield spiro-2,1'-dione derivatives (6a-e).