61862-54-2Relevant academic research and scientific papers
Ni-catalyzed homoallylation of polyhydroxy N,O- Acetals with conjugated dienes promoted by triethylborane
Mori, Takamichi,Akioka, Yusuke,Onodera, Gen,Kimura, Masanari
, p. 9288 - 9306 (2014)
In the presence of Ni-catalyst and triethylborane, N,O- Acetals prepared from glycolaldehyde and glyceraldehyde with primary amines in situ underwent homoallylation with conjugated dienes to provide 2- Amino-5-hexenols in high regio- And stereoselectivity
Nucleophilic allylation of N,O-acetals with allylic alcohols promoted by Pd/Et3B and Pd/Et2Zn systems
Yamaguchi, Yumi,Hashimoto, Mariko,Tohyama, Katsumi,Kimura, Masanari
supporting information; experimental part, p. 913 - 915 (2011/03/21)
Pd/Et3B and Pd/Et2Zn systems promote the nucleophilic allylations of 2-aminotetrahydrofuran and 2-aminotetrahydropyran with allylic alcohols to provide ω-hydroxyhomoallylamines in high yields. The transformation is applicable to the
Nickel-catalyzed multi-component connection reaction of isoprene, aldimines (lactamines), and diphenylzinc
Kojima, Keisuke,Kimura, Masanari,Ueda, Satoshi,Tamaru, Yoshinao
, p. 7512 - 7520 (2007/10/03)
Ni(acac)2 catalyzes the four-component connection reaction of diphenylzinc, isoprene, aromatic aldehydes, and aromatic amines in this order and provides stereochemically homogeneous (E)-1-arylamino-1-aryl-3-methyl-5-phenyl-3-pentenes (1) in excellent yields. Aliphatic aldehydes react similarly and give (E)-1-arylamino-1-alkyl-3-methyl-5-phenyl-3-pentenes (1) in slightly reduced yields. When the alkyl groups are bulky, in addition to 1 are formed (E)-1-arylamino-1-alkyl-4-methyl-5-phenyl-3-pentenes (1′) as the minor products. Lactamines prepared in situ from five- and six-membered lactols and aromatic amines are more reactive than alkyl aldehyde aldimines and furnish (E)-4-arylamino-6-methyl-8-phenyl-6-octen-1-ols (4) and (E)-5-arylamino-7-methyl-9- phenyl-7-nonen-1-ols (5), respectively, in good yields with excellent E-stereoselectivity.
