6187-89-9

Usage

InChI:InChI=1/C8H7NS/c1-6-7-4-2-3-5-8(7)10-9-6/h2-5H,1H3

Upstream product

• 462-80-6 benzyne 
• 5728-21-2 3,4-dimethyl-1,2,5-thiadiazole 
• 352427-09-9 tert-Butyl [({[2-(phenylsulfanyl)phenyl]ethylidene}amino)oxy]peracetate 
• 70744-47-7 (p-methoxyphenyl)tri-n-butylstannane 

Downstream Products

• 35386-77-7 3-methyl-7-nitro-1,2-benzisothiazole 
• 35272-19-6 3-methyl-5-nitro-1,2-benzisothiazole 
• 59057-83-9 3-(bromomethyl)benzoisothiazole 

Relevant academic research and scientific papers

Mobilizing Cu(I) for carbon-carbon bond forming catalysis in the presence of thiolate. Chemical mimicking of metallothioneins

Copper(I) is rendered catalytically viable in the presence of thiolate by the design of a small molecule chemical analogue of the metallothionein system in which an N-O reactant serves the same conceptual purpose of the S-S reactant of the biological system.

Thermal decomposition of tert-butyl ortho-(phenylsulfanyl)- and ortho-(phenylsulfonyl)phenyliminoxyperacetates: The reactivity of thio-substituted iminyl radicals

Some ortho-(phenylsulfanyl)- and ortho-(phenylsulfonyl)-substituted phenyliminyl radicals have been generated by thermal decomposition of suitable tert-butyl iminoxyperacetates. The sulfanyl-substituted iminyls showed no tendency to give either 1,7- or 1,

Gas-phase cyclisation reactions of 1-(2-arylthiophenyl)alkaniminyl and 2-(aryliminomethyl)thiophenoxyl radicals

Flash vacuum pyrolysis (FVP) of the oxime ethers 12-14 and of the sulfides 18-20 at 650°C (10-2-10-3 Torr) gave products derived from the corresponding iminyl and thiophenoxyl radicals. In all cases, benz[d]isothiazoles (e.g., 26) are formed as major products via SHi mechanisms though the yields are greatest with the iminyl precursors. Alternative pathways observed from the thiophenoxyls in specific cases include the formation of the anilinobenzothiophene 36 and of dibenzothiophene 23, via an SHi process and a spirodienyl rearrangement, respectively. There is no evidence for signicant interconversion of the iminyl and thiophenoxyl species.

Novel Benzyne Additions to the 1,2,5-Thiadiazole and 1,2,5-Selenadiazole Ring Systems

Novel modes of benzyne addition to 3,4-dimethyl-1,2,5-thiadiazole and 3,4-dimethyl-1,2,5-selenadiazole afford methyl derivatives of three heterocyclic systems: quinoxaline, 1,2-benzisothiazole, and 1,3-benzoselenazole respectively.