61871-81-6 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-(2-amino-5-methylphenyl)-2-phenylis used as an intermediate in the synthesis of various organic compounds for pharmaceutical applications. Its unique chemical structure allows it to be a key component in the development of new drugs and medications.
Used in Medicinal Chemistry Research:
Ethanone, 1-(2-amino-5-methylphenyl)-2-phenylis used as a research compound in medicinal chemistry. Its properties and interactions with other molecules can provide valuable insights into the development of new therapeutic agents and drug delivery systems.
Used in Organic Synthesis:
Ethanone, 1-(2-amino-5-methylphenyl)-2-phenylis used as a reagent in organic synthesis, allowing for the creation of a wide range of chemical compounds with potential applications in various industries, including pharmaceuticals, materials science, and more. Its versatility as a building block in chemical reactions makes it an important tool in the synthesis of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 61871-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,8,7 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 61871-81:
(7*6)+(6*1)+(5*8)+(4*7)+(3*1)+(2*8)+(1*1)=136
136 % 10 = 6
So 61871-81-6 is a valid CAS Registry Number.
61871-81-6Relevant academic research and scientific papers
One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene
Lee, Seok Beom,Jang, Yoonkyung,Ahn, Jiwon,Chun, Simin,Oh, Dong-Chan,Hong, Suckchang
supporting information, p. 8382 - 8386 (2020/11/18)
Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates.
A highly effective one-pot synthesis of quinolines from 2-alkynylnitrobenzenes
Okuma, Kentaro,Ozaki, Saori,Seto, Jun-Ichi,Nagahora, Noriyoshi,Shioji, Kosei
experimental part, p. 935 - 942 (2010/09/18)
A highly effective one-pot synthesis of poly-substituted quinolines from 2-alkynylnitrobenzenes using inexpensive reagents has been developed. Reaction of 2-alkynylnitrobenzenes with Sn/HCl in EtOH resulted in the formation of 2-aminophenyl ketones and subsequently condensed in situ with ketones to form tri-substituted quinolines in 80-97% yields.
