618881-57-5

Basic information

• Product Name: 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-ynoic acid tert-butyl ester
• Synonyms: 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-ynoic acid tert-butyl ester
• CAS NO: 618881-57-5
• Molecular Weight: 403.562
• Mol File: 618881-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-ynoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-ynoic acid tert-butyl ester(618881-57-5)
• EPA Substance Registry System: 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-ynoic acid tert-butyl ester(618881-57-5)

Safety Data

• Hazardous Substances Data: 618881-57-5(Hazardous Substances Data)

Upstream product

• 618881-55-3 (R)-N-(1-benzyloxymethyl-2-methylpropyl)hydroxylamine 
• 144570-07-0 O-Benzyl-(D)-valinol 
• 100-44-7 benzyl chloride 
• 4276-09-9 (R)-2-amino-3-methylbutanol 
• 13831-03-3 tert-butyl prop-2-ynoate 
• 618881-56-4 (R)-(1-benzyloxy-3-methyl-2-butyl)(3-methylbutylidene)amine N-oxide 

Downstream Products

• 618881-62-2 5-[1-((1-benzyloxymethyl-2-methylpropyl)hydroxyamino)-3-methylbutyl]-2,2-dimethyl[1,3]dioxolane-4-carboxylic acid [1-(8-hydroxy-1-oxoisochroman-3-yl)-3-methylbutyl]amide 
• 618881-61-1 6-(1-benzyloxymethyl-2-methylpropyl)-7-isobutyl-2,2-dimethyl-tetrahydro-1,3,5-trioxa-6-azainden-4-one 
• 618881-60-0 2-(1-benzyloxymethyl-2-methylpropyl)-3-isobutyl-4,5-dihydroxy-2,3-dihydro-[1,2]oxazine-6-one 
• 1027724-45-3 (Z)-(S)-4-[((R)-1-Benzyloxymethyl-2-methyl-propyl)-hydroxy-amino]-6-methyl-hept-2-enoic acid 
• 618881-59-7 2-(1-benzyloxymethyl-2-methylpropyl)-3-isobutyl-2,3-dihydro-[1,2]oxazine-6-one 
• 618881-58-6 4-[(1-benzyloxymethyl-2-methylpropyl)hydroxyamino]-6-methylhept-2-enoic acid tert-butyl ester 

Relevant articles and documents

Asymmetric Total Synthesis and Stereochemical Elucidation of the Antitumor Agent PM-94128

(Equation presented) PM-94128, a novel depsipeptide antitumor agent, has been synthesized for the first time through a highly stereocontrolled route. The key steps for the synthesis of the dihydroxyamino acid moiety involve a diastereoselective addition of tert-butyl lithiopropiolate to a chiral nitrone and a 2,3-dihydro[1,2]oxazin-6-one dihydroxylation. The synthesis serves to define the relative as well as the absolute configuration of the natural product (bearing five stereogenic centers).