618890-98-5Relevant academic research and scientific papers
The first synthesis of novel 7-oxo-7H-pyrrolo[3,2-d]pyrimidine 5-oxides from 1-(5-nitro-6-pyrimidinyl)-2-arylacetylenes
Susvilo, Inga,Brukstus, Algirdas,Tumkevicius, Sigitas
, p. 1151 - 1152 (2003)
Palladium-catalysed reaction of 4-amino-6-chloro-5-nitropyrimicline with arylacetylenes affords the corresponding 1-(4-amino-5-nitro-6-pyrimidinyl)-2-arylacetylenes, which in dry pyricline undergo smooth cyclisation to give 4-amino-6-aryl-7-oxo-7H-pyrrolo
Synthesis of 7-oxopyrrolo-[3,2-d]pyrimidine 5-oxides by the rearrangement of 6-alkynyl-5-nitropyrimidines
Tumkevicius,Susvilo,Brukstus
, p. 1335 - 1338 (2004)
A method is proposed for the synthesis of 6-substituted 4-amino-7-oxopyrrolo[2,3-d]pyrimidine 5-oxides which includes a Sonogashira reaction of 4-amino-6-chloro-5-nitropyrimidine with terminal alkynes and subsequent rearrangement of the 6-alkynyl-5-nitrop
Study on the reactions of 4-amino-5-nitro-6-phenylethynylpyrimidines with amines and thiols
Cikotiene, Inga,Pudziuvelyte, Erika,Brukstus, Algirdas,Tumkevicius, Sigitas
, p. 8145 - 8150 (2008/02/08)
Reactions of 4-amino-5-nitro-6-phenylethynylpyrimidines with amines and thiols have been investigated. Pyridine catalyzes rearrangement of the title compounds into 6-phenyl-7-oxo-7H-pyrrolo[3,2-d]pyrimidine-5-oxides. Primary and secondary amines and thiol
