6189-43-1

Basic information

• Product Name: 2,2,2-trifluoro-N-{1-[(3-methoxyphenyl)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl}-N-phenylacetamide
• CAS NO: 6189-43-1
• Molecular Formula: C₂₆H₂₃F₃N₂O₃
• Molecular Weight: 468.4676
• Mol File: 6189-43-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 548.1°C at 760 mmHg
• Flash Point: 285.3°C
• Density: 1.294g/cm³
• Vapor Pressure: 4.56E-12mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 2,2,2-trifluoro-N-{1-[(3-methoxyphenyl)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl}-N-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-N-{1-[(3-methoxyphenyl)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl}-N-phenylacetamide(6189-43-1)
• EPA Substance Registry System: 2,2,2-trifluoro-N-{1-[(3-methoxyphenyl)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl}-N-phenylacetamide(6189-43-1)

Safety Data

• Hazardous Substances Data: 6189-43-1(Hazardous Substances Data)

Usage

Description

2,2,2-Trifluoro-N-1-[(3-methoxyphenyl)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl-N-phenylacetamide, commonly known as MLN-4760, is a synthetic compound with significant potential in the pharmaceutical industry. It features a unique chemical structure that includes a trifluoromethyl group, an N-phenylacetamide group, and a carbonyl group attached to a tetrahydroquinoline ring, all of which contribute to its biological activity. MLN-4760 has been studied for its potential as an angiotensin II receptor antagonist, indicating its possible use in managing cardiovascular diseases such as hypertension and heart failure.

Uses

Used in Pharmaceutical Industry:
MLN-4760 is used as a potential angiotensin II receptor antagonist for the treatment of cardiovascular diseases. Its ability to block the effects of angiotensin II may help in managing conditions like hypertension and heart failure by reducing blood pressure and improving heart function.
Used in Cardiovascular Disease Treatment:
In the field of cardiovascular medicine, MLN-4760 is utilized for its potential to alleviate symptoms and complications associated with hypertension and heart failure. By antagonizing the angiotensin II receptor, it may contribute to lowering blood pressure and enhancing heart function, thus improving the overall cardiovascular health of patients.
Further research and development of MLN-4760 could pave the way for new medications specifically designed to target and treat cardiovascular conditions more effectively. Its unique chemical structure and biological activity make it a promising candidate for the development of innovative therapeutic agents in this critical area of healthcare.