61899-98-7

Upstream product

• 61899-99-8 2,6,6-trimethyl-2-hexene-1-carbonyl chloride 
• 459-80-3 geranic acid 
• 5392-40-5 (E/Z)-3,7-dimethyl-2,6-octadienal 
• 4698-08-2 (E)-geranic acid 
• 564-24-9 (+/-)-α-cyclogeranic acid 

Downstream Products

• 117760-32-4 vinyl 2,6,6-trimethylcyclohex-2-enoate carboxylate 
• 24190-29-2 (R)-α-ionone 
• 14398-36-8 (3E)-4-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-2-one 
• 143605-77-0 Acetic acid 3-hydroxy-1-methyl-3-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-propyl ester 
• 143605-76-9 Acetic acid 3-hydroxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 
• 143605-75-8 Acetic acid 3-benzyloxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 
• 143605-73-6 3-(benzyloxy)-1-(2,6,6-trimethylcyclohex-2-enyl)butan-2-one 
• 143605-73-6 3-Benzyloxy-1-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-butan-1-one 
• 143605-74-7 3-Benzyloxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butan-1-ol 
• 143605-74-7 3-Benzyloxy-1-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-butan-1-ol 
• 143605-79-2 2,2-Dimethyl-propionic acid 3-hydroxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 
• 143605-79-2 2,2-Dimethyl-propionic acid 3-hydroxy-1-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 
• 143605-80-5 3-oxo-1-(2,6,6-trimethylcyclohex-2-enyl)butyl 2,2-dimethylpropanoate 
• 143605-80-5 2,2-Dimethyl-propionic acid 3-oxo-1-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 

Relevant academic research and scientific papers

Method for synthesizing beta-damascenone

The invention discloses a method for synthesizing beta-damascenone. The method mainly comprises the following steps: oxidizing citral through sodium chlorite; carrying out catalytic cyclization through concentrated phosphoric acid to obtain alpha-cyclogeranic acid; eliminating the alkalinity of the alpha-cyclogeranic acid under the action of thionyl chloride to obtain cyclogeranenone; carrying outaddition on the cyclogeranenone and allylmagnesium chloride and carrying out acidic isomerization to obtain alpha-damascenone; carrying out epoxidation on the alpha-damascenon through peroxyacetic acid, and carrying out alkaline ring opening through potassium carbonate; catalytically heating and dehydrating through para-toluenesulfonic acid to obtain the beta-damascenone. The method disclosed bythe invention has the advantages that raw materials are cheap and easy to obtain, reaction conditions are moderate and the operation is simple and convenient; another useful spice alpha-damascenone can be synchronously synthesized and the method is a method which is suitable for industrial production of the beta-damascenone.

HETEROCUMULENES IN ACYLATION REACTIONS. 1. MECHANISM OF ACID HYDROLYSIS OF 2,6,6-TRIMETHYL-1-CARBONYLCYCLOHEX-2-ENE AND ITS THIO AND N-ISOPROPYLIMINO ANALOGS

It was established that γ-protonation of the substrate takes place preferentially during the acid hydrolysis of 2,6,6-trimethyl-1-carbonylcyclohex-2-ene and its thio and N-isopropylimino analogs.The contribution from γ-protonation increases with increase in the polarity of the medium, the activity of H+, and the electronegativity of the heteroatom.The experimental results were confirmed by theoretical calculations (MNDO).