619254-45-4Relevant academic research and scientific papers
Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: Synthesis and biological evaluation
Micheli, Fabrizio,Pasquarello, Alessandra,Tedesco, Giovanna,Hamprecht, Dieter,Bonanomi, Giorgio,Checchia, Anna,Jaxa-Chamiec, Albert,Damiani, Federica,Davalli, Silvia,Donati, Daniele,Gallotti, Chiara,Petrone, Marcella,Rinaldi, Marilisa,Riley, Graham,Terreni, Silvia,Wood, Martyn
, p. 3906 - 3912 (2008/12/21)
Within the continuous quest for the discovery of novel compounds able to treat anxiety and depression, the generation of a pharmacophore model for 5-HT2C receptor antagonists and the discovery of a new class of potent and selective 5-HT2C
COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF
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Page 16-17, (2010/02/08)
Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed: wherein Q is phenyl or a 6-membered heteroaromatic group containing at least one nitrogen atom; A is -(CH2-CH2)-, -(CH=CH)-, -(CH2)
COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF
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Page 17, (2010/02/09)
Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed: wherein R1 is halogen, cyano, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkyloxy, C1-6alkoxy, C1 6alkylthio, hydroxy, amino, mono or di C1 6alkylamino, an N-linked 4 to 7 memb
COMPOUNDS HAVING AFFINITY AT 5HT2C RECEPTOR AND USE THEREOF IN THERAPY
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Page/Page column 31, (2008/06/13)
Compounds of formula (I) or a pharmaceutically acceptable salt thereof are disclosed: wherein R1 is hydrogen, hydroxy, fluoro, chloro, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkyloxy, C1-6alkoxy or haloC
