619334-28-0 Usage
General Description
6-(2-FURYL)NICOTINONITRILE is a chemical compound that belongs to the class of heterocyclic compounds. It is a derivative of both furan and nicotinonitrile, and it is commonly used in organic synthesis and pharmaceutical research. 6-(2-FURYL)NICOTINONITRILE has potential applications in the development of new drugs and agrochemicals due to its unique chemical structure and properties. Additionally, it is used as a building block in the synthesis of various bioactive molecules and pharmaceutical intermediates. The presence of both furan and nicotinonitrile moieties in its structure gives 6-(2-FURYL)NICOTINONITRILE interesting reactivity and potential for diverse chemical reactions, making it a valuable compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 619334-28-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,9,3,3 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 619334-28:
(8*6)+(7*1)+(6*9)+(5*3)+(4*3)+(3*4)+(2*2)+(1*8)=160
160 % 10 = 0
So 619334-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H6N2O/c11-6-8-3-4-9(12-7-8)10-2-1-5-13-10/h1-5,7H
619334-28-0Relevant articles and documents
Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model
Depauw, Sabine,Lambert, Mélanie,Jambon, Samy,Paul, Ananya,Peixoto, Paul,Nhili, Raja,Marongiu, Laura,Figeac, Martin,Dassi, Christelle,Paul-Constant, Charles,Billoré, Benjamin,Kumar, Arvind,Farahat, Abdelbasset A.,Ismail, Mohamed A.,Mineva, Ekaterina,Sweat, Daniel P.,Stephens, Chad E.,Boykin, David W.,Wilson, W. David,David-Cordonnier, Marie-Hélène
, p. 1306 - 1329 (2019/02/14)
Most transcription factors were for a long time considered as undruggable targets because of the absence of binding pockets for direct targeting. HOXA9, implicated in acute myeloid leukemia, is one of them. To date, only indirect targeting of HOXA9 expres
