61941-60-4

Upstream product

• 61941-59-1 methyl 2-dimethylamino-3-benzoylphenylacetate 
• 61941-57-9 2-amino-3-benzoylbenzeneacetic acid,ethyl ester 
• 80726-62-1 (3-Benzoyl-2-dimethylamino-phenyl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

Antiinflammatory Agents. 2. Syntheses and Antiinflammatory Activity of Substituted 2-Aminophenylacetic Acid Derivatives

Several substituted 2-aminophenylacetic acid derivatives were prepared and tested for in vitro prostaglandin synthetase inhibition and for in vivo antiinflammatory activity.The 2-amino substituent is beneficial to potency in the inhibition of prostaglandin synthetase for the 3-phenoxy, 4-phenyl, and 3-benzoyl series, but only 3-benzoyl series shows increased antiinflammatory potency in the in vivo assay.

Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds

Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: STR1 wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower-alkyl, sodium or potassium, R2 is hydrogen, halogen or lower alkoxy, X is h