61949-76-6

Usage

Safety Profile

A poison by intravenous and intraperitoneal routes. Questionable carcinogen. When heated to decomposition it emits toxic vapors of Clí

InChI:InChI=1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3/t17-,19-/m1/s1

Upstream product

• 51632-16-7 3-phenoxybenzyl bromide 
• 59042-49-8 cis-permethrinic acid 
• 61976-30-5 methyl 2,2-dimethyl-3-(2,2-dichloroethenyl)cyclopropane-1-carboxylate 
• 52314-67-7 permethric acid chloride 
• 13826-35-2 3-Phenoxybenzyl alcohol 
• 3586-14-9 3-phenoxytoluene 
• 55701-05-8 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid 
• 258870-57-4 3-Phenoxybenzyl iodide 
• 202519-12-8 3,3-Dichloro-5-(2,2-dichloro-vinyl)-4,4-dimethyl-dihydro-furan-2-one 
• 202519-14-0 2,2,4,6,6-pentachloro-3,3-dimethylhex-5-enoic acid nitrile 
• 63406-23-5 methyl 4,6,6-trichloro-3,3-dimethyl-5-hexenoate 
• 61820-11-9 (+/-)-cis-2,2-dimethyl-3-(2',2'-dichlorovinyl)cyclopropanecarbonitrile 
• 61820-12-0 5-(2,2-dichlorovinyl)-4,4-dimethyl-2-oxotetrahydrofuran 
• 55667-43-1 1,1-dichloro-4-methyl-penta-1,3-diene 

Downstream Products

• 64964-54-1 (1R,3S)-3-Chloroethynyl-2,2-dimethyl-cyclopropanecarboxylic acid 3-phenoxy-benzyl ester 
• 59042-49-8 cis-permethrinic acid 
• 13826-35-2 3-Phenoxybenzyl alcohol 
• 53874-66-1 3-phenoxybenzyl chloride 
• 93388-66-0 3-phenoxybenzyl (1RS)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate 

Relevant academic research and scientific papers

IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN

The present invention describes an improved method for the synthesis of substantially pure Permethrin (1) having purity greater than 99.5% by Gas Chromatography (GC). The invention also relates to a purification process of Permethrin by recrystallization from methanol-water mixture.

N-Hydroxyphthalimide-Mediated Electrochemical Iodination of Methylarenes and Comparison to Electron-Transfer-Initiated C-H Functionalization

An electrochemical method has been developed for selective benzylic iodination of methylarenes. The reactions feature the first use of N-hydroxyphthalimide as an electrochemical mediator for C-H oxidation to nonoxygenated products. The method provides the basis for direct (in situ) or sequential benzylation of diverse nucleophiles using methylarenes as the alkylating agent. The hydrogen-atom transfer mechanism for C-H iodination allows C-H oxidation to proceed with minimal dependence on the substrate electronic properties and at electrode potentials 0.5-1.2 V lower than that of direct electrochemical C-H oxidation.

Search for Routes of Synthesis of Permethrin and Chloropermethrin Starting from Halogen-containing Alkenoic Acids

Promising procedures were developed for the synthesis of permethrin and I-chloropermethrin starting from acid chloride, nitrile, and esters of 3,3-dimethyl-2,2,4,6,6-pentachloro-5-alkenoic acid and 3,3-dimethyl-2,2,6,6-tetrachloro-5-alken-4-olide, which were prepared by adding derivatives of trichloroacetic acid to 1,1-dichloro-4-methyl-1,3-pentadiene in the presence of catalytic amounts of monovalent copper ions and amine.