61985-39-5 Usage
Derivative of indole
A heterocyclic organic compound
Use as a precursor
In the synthesis of various pharmaceuticals and agrochemicals
Serotonin receptor agonist activity
Useful in the development of new medications for the treatment of depression and other mood disorders
Potential applications
In research and development of novel chemical compounds for various industrial and medical purposes
Check Digit Verification of cas no
The CAS Registry Mumber 61985-39-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,8 and 5 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 61985-39:
(7*6)+(6*1)+(5*9)+(4*8)+(3*5)+(2*3)+(1*9)=155
155 % 10 = 5
So 61985-39-5 is a valid CAS Registry Number.
61985-39-5Relevant academic research and scientific papers
Schoepfer, Joseph,Fretz, Heinz,Gay, Brigitte,Furet, Pascal,Garcia-Echeverria, Carlos,End, Nicole,Caravatti, Giorgio
, p. 221 - 226 (1999)
Highly potent inhibitors of the Grb2-SH2 domain have been synthesized. They share the common sequence: Ac-Pmp-Ac6c-Asn-NH-(3-indolyl-propyl). Different substituents at the 3-indolyl-propylamine C-terminal group were explored to further improve the activity. This is the first example of inhibitors of SH2 domains with sub-nanomolar affinity reported to date.