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1H-Indole, 2-phenyl-3-(9H-xanthen-9-yl)- is a derivative synthesized through iodine- or indium-catalyzed nucleophilic substitution reactions between indoles and xanthen-9-ol under mild conditions, often yielding high efficiency and functional group tolerance. These methods emphasize green solvents, operational simplicity, and room-temperature compatibility, making them practical for producing such indole-xanthene hybrids. (Returned as no alternative names were provided in the abstracts.)

61995-43-5

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61995-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 61995-43-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,9 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61995-43:
(7*6)+(6*1)+(5*9)+(4*9)+(3*5)+(2*4)+(1*3)=155
155 % 10 = 5
So 61995-43-5 is a valid CAS Registry Number.

61995-43-5Relevant academic research and scientific papers

Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions

Bai, Mengjiao,Duan, Hengpan,Duan, Suyue,Miao, Weihang,Wang, Xuequan,Yang, Zhixin,Ye, Pingting

, p. 25165 - 25169 (2020)

An iodine-catalyzed nucleophilic substitution reaction of xanthen-9-ol and thioxanthen-9-ol with indoles has been developed, providing an efficient procedure for the synthesis of xanthene/thioxanthene-indole derivatives with good to excellent yields. This protocol offers several advantages, such as short reaction times, green solvent, operational simplicity, easily available catalyst and mild reaction conditions. Moreover, this method showed good tolerance of functional groups and a wide range of substrates.

Indium tris(dodecyl sulfonate) [In(DS)3]-catalyzed formation of 3-(9H-xanthen-9-yl)-1H-indole derivatives in water at room temperature

Wang, Shun-Yi,Ji, Shun-Jun

, p. 465 - 472 (2008)

In(DS)3 catalyzes formation of 9H-xanthen-9-ol with indoles at room temperature in water to afford a class of 3-(9H-xanthen-9-yl)-1H-indole derivatives in high yields. Copyright Taylor & Francis Group, LLC.

Novel reaction of indoles and pyrrole with pyrillium catalyzed by ceric ammonium nitrate (CAN)

Wang, Shun-Yi,Ji, Shun-Jun

, p. 2222 - 2226 (2008/02/10)

The reaction of xanthene derivatives with indoles and pyrrole catalyzed by CAN in methanol through SN1 reaction of pyrillium with a nucleophilic reagent afforded the corresponding indole- and pyrrole-substituted xanthene derivatives in high yields, respectively. Georg Thieme Verlag Stuttgart.

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