62002-64-6Relevant academic research and scientific papers
Transformations of electrophilic reagents in a diethyl phosphite-potassium carbonate-ethanol system
Platonov, A. Yu.,Sivakov, A. A.,Chistokletov, V. N.,Maiorova, E. D.
, p. 367 - 370 (1999)
Transformations of alkyl halides, aldehydes, and activated alkenes in a (EtO)2PHO-K2CO3-EtOH heterophase system were studied. The reactions are catalyzed by EtOK that formed and follow the known schemes of the interaction of hydrophosphoryl compounds with electrophiles.
A convenient and mild protocol for preparation of α – trimethylsilyloxyphosphonates using sulfamic acid and their oxidation to α – ketophosphonates in the presence of N-bromosuccinimide
Mitragotri, Satish D.,Kulkarni, Makarand A.,Desai, Uday V.,Wadagaonkar, Prakash P.
, (2021/10/05)
A convenient and mild protocol was developed for the trimethylsilylation of α-hydroxyphosphonates using hexamethyldisilazane as the silylating agent in the presence of sulfamic acid (SA) as a heterogeneous solid acid catalyst in dichloromethane as the rea
One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems
Prasad, Sure Siva,Singh, DIleep Kumar,Kim, Ikyon
supporting information, p. 6323 - 6336 (2019/05/24)
A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.
Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
Fathalla, Walid,Ali, Ibrahim A. I.,Pazdera, Pavel
, p. 7385 - 7395 (2018/03/01)
A series of ether phosphonates have been prepared by trichloroacetimidate and acetate coupling methods. Trichloroacetimidates or acetates were treated with primary and secondary alcohols as O-nucleophiles in the presence of catalytic TMSOTf to afford 21 examples of diethyl alkyloxy(substitutedphenyl)methyl phosphonates via C-O bond formation in 55-90% yields and short reaction time.
Efficient synthesis of α-substituted-α-arylmethyl phosphonates using trichloroacetimidate C–C coupling method
Fathalla, Walid,Pazdera, Pavel,El-Rayes, Samir,Ali, Ibrahim.A.I.
, p. 1681 - 1691 (2018/03/01)
A simple convenient protocol for the synthesis of diethyl α,α-diaryl methylphosphonate derivatives 5a-f, 6b-f, 7a-f and 8a-f, diethyl α-alkenyl α-aryl methylphosphonates 9a-d and 10a-d and α-(oxoalkyl) α-aryl methylphosphonate 11a-d and 12a-d is described. Trichloroacetimidates 3a-d were treated with activated arenes, styrene, allyltrimethylsilane or silylenol ethers C-nucleophiles in the presence TMSOTf to afford the desired products in good yields and short reaction time.
Mechanistic approach for expeditious and solvent-free synthesis of α-hydroxy phosphonates using potassium phosphate as catalyst
Kulkarni, Makarand A.,Lad, Uday P.,Desai, Uday V.,Mitragotri, Satish D.,Wadgaonkar, Prakash P.
, p. 148 - 152 (2013/04/24)
An extremely simple, high yielding, highly rapid and solvent-free protocol has been described for hydrophosphylation of aldehydes using potassium phosphate as catalyst. Easy commercial availability of the reusable catalyst, operational simplicity at ambie
Synthesis of α-hydroxyphosphonates and their antioxidant properties
Naidu, Kalla Reddi Mohan,Kumar, Krishnammagari Suresh,Arulselvan, Palanisamy,Reddy, Chinnappareddy Bhupendra,Lasekan, Ola
, p. 957 - 963 (2013/02/22)
A series of α-hydroxyphosphonates were synthesized from the reaction of aldehyde (1) with triethylphosphite (2) in the presence of oxone and evaluated for their antioxidant properties against lipid peroxidation, reduced glutathione, superoxide dismutase,
