62006-39-7

Usage

Uses

Used in Flavoring Industry:
3-N-butyl-4,5-dihydrophthalide is used as a flavoring agent for its distinctive sweet, minty, and spicy aroma, enhancing the taste profiles of various food and beverage products.
Used in Perfumery and Cosmetics Industry:
3-N-butyl-4,5-dihydrophthalide is utilized as a fragrance ingredient in perfumes and cosmetics, contributing to their unique scent profiles and providing a pleasant sensory experience for consumers.
Used in Pharmaceutical Industry:
3-N-butyl-4,5-dihydrophthalide is employed in the pharmaceutical industry for its potential therapeutic properties, including its antifungal, antibacterial, and antioxidant effects, which may contribute to the development of new treatments and medications.
Used in Neurological Disorder Treatment:
3-N-butyl-4,5-dihydrophthalide is being investigated for its potential use in the treatment of neurological disorders, suggesting a possible role in managing or alleviating symptoms associated with such conditions.
Used as an Insect Repellent:
3-N-butyl-4,5-dihydrophthalide has been studied for its potential as an insect repellent, indicating its possible application in pest control and protection against insect-borne diseases.

InChI:InChI=1/C12H16O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7,11H,2-4,6,8H2,1H3

Upstream product

• 626-99-3 1,3-butadiene-1-carboxylic acid 
• 1020260-47-2 (R)-(+)-1-ethynylpentyl 2,4-pentadienoate 
• 1020260-46-1 (S)-(-)-1-ethynylpentyl 2,4-pentadienoate 
• 117005-27-3 senkyunolide P 
• 1020260-45-0 1-ethynylpentyl 2,4-pentadienoate 

Downstream Products

• 153609-99-5 senkyunolide-J 
• 140694-58-2 Senkyunolide N 

Relevant academic research and scientific papers

PHTHALIDE DIMERS FROM LIGUSTICUM CHUANGXIONG Hort.

Two new phthalide dimers, senkyunolide O (1) and senkyunolide P (2), along with three known phthalide dimers were isolated from the rhizome of Ligusticum chuangxiong Hort.On the basis of spectral analyses and chemical methods, the structures of these compounds were determined.

Structural Reassignment of rel-(3′ Z,3 R,6 R,7 R,3a′ R,6′ R)-3,8-Dihydrodiligustilide and the Activity of Diligustilide and 3,8-Dihydro- A nd 3,8,7′,7a′-Tetrahydrodiligustilides as Progestins

Several phthalides were semisynthesized, including a 3,8-dihydrodiligustilide with progesterone-like activity, previously isolated from Ligusticum chuanxiong, the structure of which was earlier assigned to a semisynthetic product with nonidentical spectroscopic constants. The structure of this natural phthalide was reassigned with a proposal of its absolute configuration. Phthalides acted as progestins in cell viability assays, immunofluorescence microscopy, and docking analysis. Therefore, the structures for natural and semisynthetic phthalides with potential use in hormone-related therapies were reassigned.

Asymmetric synthesis and sensory evaluation of sedanenolide

The synthesis and sensory evaluation of enantiomeric sets of sedanenolide (1) and 3-butylphthalide (3) are described. The asymmetric synthesis was achieved via the intramolecular Diels-Alder reaction of chiral propargylester (5) which was prepared from optically active propargyl alcohol (4) and 2,4-pentadienoic acid. The sensory evaluation of these enantiomers revealed that there were distinct differences between their aroma character and odor threshold.