620163-19-1Relevant academic research and scientific papers
A facile asymmetric route to (-)-aphanorphine
Zhai, Hongbin,Luo, Shengjun,Ye, Chengfeng,Ma, Yongxiang
, p. 8268 - 8271 (2003)
8O-Methylaphanorphine was synthesized from 4-methoxyphenylacetaldehyde in 36% overall yield and in nine steps, featuring the formation of ring B via a Friedel-Crafts alkylative cyclization with the concomitant stereospecific introduction of the benzylic q
