62018-14-8Relevant academic research and scientific papers
Isolation and identification of an in vivo reaction product of 6 hydroxydopamine
Liang,Plotsky,Adams
, p. 581 - 583 (1977)
The product of oxidized 6 OHDA and GSH reacted in vitro has been identified by a variety of chemical and physical methods to be 2,4,5 trihydroxy 6 S (glutathionyl)phenethylamine. Its chemical properties show it easily undergoes a variety of oxidative condensations and polymerization. Its oxidized form, the p quinone, can be identified in small quantities in rat brain and mouse brain 1-3 hr after 6-OHDA injection. This is believed to be the first report of a chemically identified species resulting from the in vivo interaction of 6-OHDA with CNS tissue.
