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4-Sulphanilamidosalicylic acid, also known as sulfasalazine, is a prodrug that is primarily used in the treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. It is a combination of 5-aminosalicylic acid (5-ASA) and sulfapyridine, which is an antibacterial agent. When ingested, the compound is metabolized in the colon, where it is broken down into its two components. The 5-ASA component has anti-inflammatory properties, while the sulfapyridine has antibacterial effects. The exact mechanism of action of sulfasalazine is not fully understood, but it is believed to work by reducing inflammation and inhibiting the immune system's response in the gut. It is typically prescribed as a first-line treatment for mild to moderate cases of inflammatory bowel disease and can be taken orally in various forms, such as tablets or enemas.

6202-21-7

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6202-21-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6202-21-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,0 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6202-21:
(6*6)+(5*2)+(4*0)+(3*2)+(2*2)+(1*1)=57
57 % 10 = 7
So 6202-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H12N2O5S/c14-8-1-4-10(5-2-8)21(19,20)15-9-3-6-11(13(17)18)12(16)7-9/h1-7,15-16H,14H2,(H,17,18)

6202-21-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-4-sulfanilylamino-benzoic acid

1.2 Other means of identification

Product number -
Other names 4-sulphanilamido salicylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6202-21-7 SDS

6202-21-7Relevant academic research and scientific papers

Synthesis of sulfanilamido-naphthoquinones as potential antituberculous agents

Osman,Abdalla,Alaib

, p. 68 - 71 (2007/10/02)

p-Aminobenzoic acid, the acid hydrazides of benzoic acid, salicylic acid and isonicotinic acid, and 4,4'-diaminodiphenyl sulfone were condensed with p-aminobenzenesulfonyl chloride to give the corresponding N1-substituted sulfanilamides. These molecules were then treated with 1,4-naphthoquinone to yield 2-substituted-1,4-naphthoquinones. The partition coefficient for the substituted quinones showed, in some cases, high diffusion rates to the organic phase, benzene, from physiological Tyrode's solution. These compounds are effective in low concentration in dioxane against the human sensitive strain of Mycobacterium tuberculosis H37 Rv. Sulfanilamides obtained from p-aminosalicylic acid and thiosemicarbazide failed to react with 1,4-naphthoquinone. These sulfanilamides also showed high activity against the same Mycobacterium.

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