62036-62-8Relevant academic research and scientific papers
Alkylation of 4-Amino-3-mercapto-1,2,4-triazin-5(4H)-ones and Oxidation of the Products
Sauter, Fritz,Jordis, Ulrich,Siddiqi, Suhaib M.
, p. 2714 - 2730 (2007/10/02)
4-Amino-1,2,4-triazin-5(4H)-ones were alkylated with different alkylating agents to give N- and S-alkylated products. 4-Amino-3-methylthio-1,2,4-triazin-5(4H)-one (2a) was oxidized at position 5 to give 4-amino-3-methylthio-1,2,4-triazine-5,6(1H,4H)-dione (4) with Br2/H2O, Br2/EtOH or NBS/EtOH, while Br2/MeOH gave 4-amino-6-methoxy-3-methylthio-1,2,4-triazin-5(4H)-one (8a).
