62039-81-0 Usage
Molecular Weight
323.83 g/mol
Appearance
Yellowish solid
Solubility
Slightly soluble in water, soluble in organic solvents such as ethanol and methanol
Melting Point
236-240°C
Main Property
Entacapone is a medication used in the treatment of Parkinson's disease.
Mechanism of Action
Inhibits the enzyme catechol-O-methyltransferase (COMT), which increases the levels of dopamine in the brain.
Benefits
Alleviates symptoms of Parkinson's disease, such as tremors, stiffness, and difficulty with movement.
Administration
Typically administered orally, may be found in various pharmaceutical formulations such as tablets or capsules.
Usage
Often used in combination with other medications for Parkinson's disease, such as levodopa and carbidopa.
Check Digit Verification of cas no
The CAS Registry Mumber 62039-81-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,0,3 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 62039-81:
(7*6)+(6*2)+(5*0)+(4*3)+(3*9)+(2*8)+(1*1)=110
110 % 10 = 0
So 62039-81-0 is a valid CAS Registry Number.
62039-81-0Relevant academic research and scientific papers
Preparation of indole derivatives
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, (2008/06/13)
An improved process for preparing indole derivatives of the formula, STR1 wherein R1 and R2 each are hydrogen, halogen, C1 -C3 alkyl, C1 -C3 alkoxy, nitro, cyano or trifluoromethyl, or when taken together, form methylenedioxy; R3 is hydrogen, halogen, C1 -C3 alkyl, C1 -C3 alkoxy, nitro, cyano or dimethylamino; and R4 is hydrogen or halogen, which comprises cyclizing a compound of the formula, STR2 wherein R1, R2, R3 and R4 are as defined above, with an acidic condensing agent. The indole derivatives of the formula (I) mentioned above are useful as a key intermediate for the preparation of benzodiazepines, which are useful as tranquilizers, muscle relaxants and the like.
