62056-64-8Relevant academic research and scientific papers
Application of Diphenylphosphinic Carboxylic Mixed Anhydrides to Peptide Synthesis.
Ramage, Robert,Hopton, David,Parrott, Maxwell J.,Richardson, Reginald S.,Kenner, George W.,Moore, Geoffrey A.
, p. 461 - 470 (2007/10/02)
Diphenylphosphinic carboxylic mixed anhydrides formed in situ from Nα-protected amino acids and diphenylphosphinic chloride have been critically evaluated in peptide synthesis.Wherever possible, 32.4 MHz 31P n.m.r. spectroscopy has been employed to follow the rates of both mixed anhydride formation and aminolysis.
PEPTIDES-XXXX. SYNTHESIS OF THE 68-75 FRAGMENT OF A LYSOZYME ANALOGUE
Galpin, I.J.,Hudson, D.,Jackson, A.G.,Kenner, G.W.,Ramage, R.
, p. 2255 - 2257 (2007/10/02)
The 68-75 subfragment has been prepared by a 4+4 fragment condensation using DCCI/HOBt.The constituent 68-71 and 72-75 fragments being prepared stepwise by the pivalic mixed anhydride method.The octapeptide prepared by this approach was shown to be identi
