620593-96-6

Upstream product

• 19924-43-7 3-methoxyphenylacetonitrile 
• 620593-93-3 4-hydroxy-2-(2-hydroxyethyl)-2-(3-methoxyphenyl)butanenitrile 
• 850884-29-6 4-(3-methoxyphenyl)-1-pyrimidin-2-ylpiperidine-4-carbonitrile 

Downstream Products

• 1176965-10-8 4-(3-methoxyphenyl)-1-(pyridin-2-yl)piperidine-4-carbonitrile 
• 850884-29-6 4-(3-methoxyphenyl)-1-pyrimidin-2-ylpiperidine-4-carbonitrile 
• 620593-90-0 1-benzoyl-4-(3-methoxyphenyl)piperidine-4-carbonitrile 
• 35592-42-8 4-(3-methoxyphenyl)-1-[(4-methylphenyl)-sulfonyl]piperidine-4-carbonitrile 
• 109254-16-2 1-benzyl-4-(3-methoxy-phenyl)-piperidine-4-carbonitrile 

Relevant academic research and scientific papers

NOVEL PIPERIDINE DERIVATIVE

The invention provides a compound of the following formula (1): wherein m, n, and p are independently an integer of 0 - 4, provided 3 ≤ m + n ≤ 8; X is nitrogen atom or a group of the formula: C-R15; Y is a substituted or unsubstituted aromatic group, etc.; R15, R1, R2, R3, R4 , R5, R6 and R7 are hydrogen atom, a substituted or unsubstituted alkyl group, etc.; and Z is hydrogen atom, cyano group, etc., or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which exhibits an action for enhancing LDL receptor expression, and is useful as a medicament for treating hyperlipidemia, atherosclerosis, etc.

NOVEL SULFONAMIDE DERIVATIVE

A compound of the formula (1): wherein m, n and p is independently an integer of 0 to 4 with the proviso that 3 a?| m + n a?| 8; X is the formula: NR4, etc.; R1, R3 and R4 are a substituted or unsubstituted aryl group, etc.; R2 is a hydrogen atom, etc.; a, b, c, d, e and f are a hydrogen atom or a substituted or unsubstituted alkyl group, etc.; Y is the formula: -SO2-, etc.; and Z is an oxygen atom, etc.; or a prodrug thereof or a pharmaceutically acceptable salt of the same has an activity of potentiating an expression of a low density lipoprotein receptor and thus is useful as an agent for treating hyperlipidemia or arteriosclerosis.