620628-84-4

Basic information

• Product Name: N-[2-(benzothiazole-2-sulfonylamino)-ethyl]-N-{[2-N-(benzhydryloxycarbonyl)-guanin-9-yl]-acetyl}-glycine ethyl ester
• Synonyms: N-[2-(benzothiazole-2-sulfonylamino)-ethyl]-N-{[2-N-(benzhydryloxycarbonyl)-guanin-9-yl]-acetyl}-glycine ethyl ester
• CAS NO: 620628-84-4
• Molecular Weight: 744.809
• Mol File: 620628-84-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[2-(benzothiazole-2-sulfonylamino)-ethyl]-N-{[2-N-(benzhydryloxycarbonyl)-guanin-9-yl]-acetyl}-glycine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(benzothiazole-2-sulfonylamino)-ethyl]-N-{[2-N-(benzhydryloxycarbonyl)-guanin-9-yl]-acetyl}-glycine ethyl ester(620628-84-4)
• EPA Substance Registry System: N-[2-(benzothiazole-2-sulfonylamino)-ethyl]-N-{[2-N-(benzhydryloxycarbonyl)-guanin-9-yl]-acetyl}-glycine ethyl ester(620628-84-4)

Safety Data

• Hazardous Substances Data: 620628-84-4(Hazardous Substances Data)

Upstream product

• 620628-51-5 N-[2-(benzothiazole-2-sulfonylamino)ethyl]glycine ethyl ester 
• 169287-79-0 2-(2-(benzhydryloxycarbonylamino)-guanin-9-yl)acetic acid 

Downstream Products

• 620629-00-7 N-[2-(benzothiazole-2-sulfonylamino)ethyl]-N-{[2-N-(benzhydryloxycarbonyl)guanin-9-yl]acetyl}glycine 

Relevant articles and documents

Peptide nucleic acid synthesis by novel amide formation

Synthesis of self-activated peptide nucleic acid (PNA) monomers and an efficient method for PNA synthesis using a benzothiazole-2-sulfonyl (Bts) group as an amine-protecting group as well as an acid-activating group are reported. Couplings were complete w

PNA monomer and precursor

This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oligomers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: wherein E is nitrogen or C—R′; J is sulfur or oxygen; R′, R1, R2, R3, R4 is independently H, halogen, alkyl, nitro, nitrile, alkoxy, halogenated alkyl, halogenated alkoxy, phenyl or halogenated phenyl, R5 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases in the presence of thiol.