62063-02-9

Usage

Uses

Used in Organic Synthesis:
1H-Pyrazole-3,5-diamine,4-nitro-(9CI) is utilized as a key intermediate in organic synthesis for the preparation of various chemical compounds. Its unique structure allows for the formation of diverse derivatives, expanding the scope of chemical reactions and products that can be synthesized.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-Pyrazole-3,5-diamine,4-nitro-(9CI) is employed as a building block for the development of pharmaceuticals. Its incorporation into drug molecules can potentially enhance their therapeutic properties, such as improving binding affinity to target proteins or modulating pharmacokinetic profiles.
Used in Agrochemicals Production:
1H-Pyrazole-3,5-diamine,4-nitro-(9CI) also finds application in the agrochemical industry, where it serves as a precursor for the synthesis of agrochemicals. Its use in this sector can contribute to the development of novel pesticides or herbicides with improved efficacy and selectivity.
Used as a Research Tool in Biochemistry and Pharmacology:
Due to its distinctive chemical properties, 1H-Pyrazole-3,5-diamine,4-nitro-(9CI) is used as a research tool in biochemical and pharmacological studies. It can aid in understanding the mechanisms of action of various biological processes and in the discovery of new therapeutic targets or lead compounds for drug development.

Upstream product

• 54660-12-7 4-chloro-6-dimethylamino-5-nitropyrimidine 
• 16350-69-9 α-amino-α-dimethylamino-α-cyano-α-nitroethylene 
• 90860-50-7 4-dimethylamino-6-methoxy-5-nitropyrimidine 
• 54660-14-9 4-(6-chloro-5-nitropyrimidin-4-yl)morpholine 
• 104-94-9 4-methoxy-aniline 
• 16350-44-0 1-(N-Methylamino)-1-amino-2-cyan-2-nitroethylen 
• 25713-54-6 1,1-Diamino-2-cyan-2-nitroethylen 

Downstream Products

• 292600-38-5 1-acetamido-3,5-diamino-4-nitropyrazole 

Relevant academic research and scientific papers

Highly polarized enamines. 3. Study of the spatial structure of α,α-diamino-β-cyano-β-nitroethylene derivatives

The spatial structure of various derivatives of α,α-diamino-β-cyano-β-nitroethylene has been investigated using 1H and 13C NMR spectroscopy. It was shown that the configuration of the investigated push-pull enamines is determined by the possibility of creating an intramolecular hydrogen bond between NH and NO2 groups or by steric interactions. A series of 3,5-diamino-5-nitropyrazole derivatives has been synthesized by reacting these amines with hydrazine hydrate. 1997 Plenum Publishing Corporation.

Anti-coxsackievirus B3 activity of 2-amino-3-nitropyrazolo[1,5-a] pyrimidines and their analogs

The synthesis of the 2-amino-3-nitropyrazolo[1,5-a]pyrimidines with anti-coxsackievirus B3 activity is described. A novel class of 2-amino-4-nitropyrazolo[1,5-a]pyrimidines has been identified as potent inhibitors of coxsackievirus B3 replication. The syn

New synthetic route to diaminonitropyrazoles as precursors of energetic materials

Treatment of nitropyrimidine derivatives with (N-substituted) hydrazines (2 equiv.) gave 1-(substituted)-3,5-diamino-4-nitropyrazole, providing a very mild conversion of pyrimidines into pyrazoles. This reaction provided a convenient route to precursors for new efficient and insensitive explosives.

Investigation of the reaction of 3,5-diamidino-4-nitropyrazole with amines

The interaction of 3,5-bis(N,N-dimethylaminomethylene)amino-1-methyl-4-nitropyrazole with amines proceeds regioselectively with the formation of 3-amino-5-(N,N-dimethylaminomethylene)amino-1- methyl-4-nitropyrazole. Amines are converted in this way into N