62071-40-3 Usage
General Description
4-(Tetrahydro-pyran-4-yl)-phenylamine, also known as THP-phenylamine, is a chemical compound consisting of a phenylamine group attached to a tetrahydro-pyran ring. It is commonly used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. THP-phenylamine has shown potential as a ligand in transition metal-catalyzed cross-coupling reactions, and has been studied for its potential application in organic and medicinal chemistry. 4-(TETRAHYDRO-PYRAN-4-YL)-PHENYLAMINE is also of interest for its potential biological activity, and is being investigated for its potential use as a drug candidate.
Check Digit Verification of cas no
The CAS Registry Mumber 62071-40-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,0,7 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 62071-40:
(7*6)+(6*2)+(5*0)+(4*7)+(3*1)+(2*4)+(1*0)=93
93 % 10 = 3
So 62071-40-3 is a valid CAS Registry Number.
62071-40-3Relevant articles and documents
P2Y1 receptor antagonists as novel antithrombotic agents
Pfefferkorn, Jeffrey A.,Choi, Chulho,Winters, Thomas,Kennedy, Robert,Chi, Liguo,Perrin, Lisa A.,Lu, Gina,Ping, Yun-Wen,McClanahan, Tom,Schroeder, Richard,Leininger, Michael T.,Geyer, Andrew,Schefzick, Sabine,Atherton, James
scheme or table, p. 3338 - 3343 (2009/04/06)
The P2Y1 and P2Y12 purinergic receptors are responsible for mediating adenosine diphosphate (ADP) dependent platelet aggregation. Evidence from P2Y1 knockout studies as well as from nucleotide-based small molecule P2Y1 antagonists has suggested that the antagonism of this receptor may offer a novel and effective method for the treatment of thrombotic disorders. Herein, we report the identification and optimization of a series of non-nucleotide P2Y1 antagonists that are potent and orally bioavailable.
