620972-18-1

Upstream product

• 76-83-5 trityl chloride 
• 1604-44-0 N-α-trifluoroacetyl-L-histidine methyl ester 

Downstream Products

• 620972-24-9 3-(3-benzyl-2-cyclopentyl-3H-imidazol-4-yl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 620972-23-8 3-(3-benzyl-2-tert-butyl-3H-imidazol-4-yl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 620972-26-1 3-(3-benzyl-2-cyclopropyl-3H-imidazol-4-yl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 620972-27-2 3-(3-benzyl-2-isopropyl-3H-imidazol-4-yl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 620972-19-2 α-N-trifluoroacetyl-3-benzyl-L-histidine methyl ester 

Relevant academic research and scientific papers

Trityl-directed regiospecific synthesis of 2,3-disubstituted bioimidazoles

We report an efficient trityl-directed regiospecific synthesis of 2,3-disubstituted-L-histdines and 2,3-disubstituted histamines starting from α-N-trifluoroacetyl-L-histidine methyl ester and α-N-trifluoroacetylhistamine respectively in five steps.