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(5E)-5-(2,5-dimethyl-1-[4-(morpholin-4-yl)phenyl]-1H-pyrrol-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is a thiazolidinone compound with a molecular formula of C20H22N4O2S2. It is a potent and selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which is involved in the conversion of cortisone to cortisol.

6212-25-5

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6212-25-5 Usage

Uses

Used in Pharmaceutical Industry:
(5E)-5-(2,5-dimethyl-1-[4-(morpholin-4-yl)phenyl]-1H-pyrrol-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is used as a therapeutic agent for the treatment of metabolic disorders such as diabetes and obesity. Its inhibition of 11β-HSD1 enzyme helps regulate cortisol levels, which can improve insulin sensitivity and reduce inflammation associated with these conditions.
Used in Inflammatory and Immune-Related Conditions:
(5E)-5-(2,5-dimethyl-1-[4-(morpholin-4-yl)phenyl]-1H-pyrrol-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is used as a potential treatment for inflammatory and immune-related conditions. Its ability to modulate cortisol levels may help in managing inflammation and immune responses, offering a new approach to treating such conditions.
Research and Development:
(5E)-5-(2,5-dimethyl-1-[4-(morpholin-4-yl)phenyl]-1H-pyrrol-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is used as a target for drug development in the pharmaceutical industry. Ongoing research aims to further explore its potential applications and optimize its therapeutic effects for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 6212-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,1 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6212-25:
(6*6)+(5*2)+(4*1)+(3*2)+(2*2)+(1*5)=65
65 % 10 = 5
So 6212-25-5 is a valid CAS Registry Number.

6212-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (5E)-5-[[2,5-dimethyl-1-(4-morpholin-4-ylphenyl)pyrrol-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6212-25-5 SDS

6212-25-5Upstream product

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