62145-07-7 Usage
General Description
11-keto fluprostenol is a synthetic prostaglandin analog that acts as a potent ocular hypotensive agent. It is used in the treatment of glaucoma and ocular hypertension to reduce intraocular pressure by increasing the outflow of aqueous humor. 11-keto fluprostenol works by binding to prostaglandin receptors in the eye, specifically the FP receptor, which leads to relaxation of the ciliary muscle and increased uveoscleral outflow. It is available as an ophthalmic solution for topical administration and has shown to be effective in lowering intraocular pressure with minimal systemic side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 62145-07-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,1,4 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 62145-07:
(7*6)+(6*2)+(5*1)+(4*4)+(3*5)+(2*0)+(1*7)=97
97 % 10 = 7
So 62145-07-7 is a valid CAS Registry Number.
62145-07-7Relevant articles and documents
9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma
-
Page/Page column 17-18, (2010/11/30)
9,11-Cycloendoperoxide derivatives of biologically active prostaglandin analogs, and particularly of the ocular hypotensive drugs Bimatoprost, Latanaprost, Unoprostone, Travoprost and prostaglandin H2 1-ethanolamide or of structurally closely related analogs, are pro-drugs which hydrolyze under physiological conditions to provide prostaglandin analogues that are capable of providing sustained ocular and other in vivo concentrations of the respective drugs. The compounds of the invention have the formula shown below where the variables have the meaning defined in the specification.
