62153-40-6Relevant academic research and scientific papers
The Generation of Difluoroketenimine and Its Application in the Synthesis of α,α-Difluoro-β-amino Amides
Zhang, Rui,Zhang, Zhikun,Zhou, Qi,Yu, Lefei,Wang, Jianbo
supporting information, p. 5744 - 5748 (2019/03/28)
Fluorine-containing β-amino acids and their derivatives have attracted significant attention due to their importance in life sciences. Herein the previously unknown difluoroketenimine, the analogue of the elusive difluoroketene, has been generated by the
Reaction between Aldehyde Oximes and Methanesulphinyl Chloride
Banks, Malcolm R.,Brown, Charles,Hudson, Robert F.,Record, Keith A. F.
, p. 1501 - 1508 (2007/10/02)
The reactions of several (E)- and (Z)-benzaldehyde oximes with methanesulphinyl chloride at -70 deg C give benzaldehyde O-methylsulphinyloxime intermediates.These rearrange above 0 deg C to give the corresponding sulphonylimines in good yield, accompanied by minor products including nitriles and products derived from the decomposition of methanesulphinic acid.N.m.r. spectra (1H and 13C) show strong polarizations in the sulphonylimines, indicating a radical-cage mechanism.Further evidence for the involvement of radicals comes from the observation of strong e.s.r. signals.Kinetic measurements of the activation parameters support the conclusions that homolytic dissociation of the N-O bond is the major pathway in this rearrangement.
Removal of Toluene-p-sulphonyl Groups from Sulphonamides. Part 4. Synthesis of Phenylglyoxal Imine Monomers
McKay, William R.,Proctor, George R.
, p. 2435 - 2442 (2007/10/02)
Syntheses and reactions of N-tosylphenacylamines with bases have been systematically examined.Monomeric C-methoxy-imines are available from some of these reactions.C-Methoxyphenacylarylamines, made by two routes, were converted into monomeric imines on treatment with noble-metal catalysts, The boron trifluoride-catalysed reactions of aryl aldehydes with sulphonamides provide a new and convenient route to N-sulphonylarylimines.
