62155-44-6

Basic information

• Product Name: 1-benzyl-4-butylbenzene
• Synonyms: 1-Benzyl-4-butylbenzene; 4-Butyldiphenylmethane; benzene, 1-butyl-4-(phenylmethyl)-
• CAS NO: 62155-44-6
• Molecular Formula: C₁₇H₂₀
• Molecular Weight: 224.3407
• Mol File: 62155-44-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: -34.95 °C
• Boiling Point: 326.4°C at 760 mmHg
• Flash Point: 158.5°C
• Density: 0.955g/cm³
• Vapor Pressure: 0.000412mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 1-benzyl-4-butylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-butylbenzene(62155-44-6)
• EPA Substance Registry System: 1-benzyl-4-butylbenzene(62155-44-6)

Safety Data

• Hazardous Substances Data: 62155-44-6(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 2116-36-1 1-benzyl-4-bromo-benzene 
• 20651-67-6 4-butyliodobenzene 
• 188404-92-4 (o-methylphenyl)dimethylsilane 
• 104-51-8 1-butylbenzene 
• 100-51-6 benzyl alcohol 
• 14534-83-9 4-butyl-tri-N-methyl-anilinium; iodide 
• 6921-34-2 benzylmagnesium chloride 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Water and Sodium Chloride: Essential Ingredients for Robust and Fast Pd-Catalysed Cross-Coupling Reactions between Organolithium Reagents and (Hetero)aryl Halides

Direct palladium-catalysed cross-couplings between organolithium reagents and (hetero)aryl halides (Br, Cl) proceed fast, cleanly and selectively at room temperature in air, with water as the only reaction medium and in the presence of NaCl as a cheap additive. Under optimised reaction conditions, a water-accelerated catalysis is responsible for furnishing C(sp3)–C(sp2), C(sp2)–C(sp2), and C(sp)–C(sp2) cross-coupled products, in competition with protonolysis, within a reaction time of 20 s, in yields of up to 99 %, and in the absence of undesired dehalogenated/homocoupling side products even when challenging secondary organolithiums serve as the starting material. It is worth noting that the proposed protocol is scalable and the catalyst and water can easily and successfully be recycled up to 10 times, with an E-factor as low as 7.35.

Synthesis of diarylmethanes via a Friedel-Crafts benzylation using arenes and benzyl alcohols in the presence of triphenylphosphine ditriflate

Triphenylphosphine ditriflate (TPPD) was found to be an efficient promoter for the Friedel-Crafts benzylation of arenes with benzyl alcohols in CH 2Cl2 at room temperature. The good yields, the 1:1 molar ratio of arene and benzyl alcohol, the benzylation of chlorobenzene as a nonactivated aromatic compound at room temperature, and no by-product formation are the main advantages of this procedure.

Nickel-induced Conversion of Carbon-Nitrogen into Carbon-Carbon Bonds. One step Transformations of Aryl, Quaternary Ammonium Salts into Alkylarenes and Biaryls

Aryltrimethylammonium iodides are shown to undergo reaction with Grignard reagents under phosphinate-ligated, low-valent nickel catalysis with the formation of alkylarenes and biaryls.