62160-01-4 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-amino-3-carbamoyl-1H-pyrazol-5-yl)-1,4-anhydropentitol is used as an antimicrobial agent for the treatment of bacterial infections. Its ability to inhibit bacterial protein synthesis makes it a promising candidate for the development of new antibiotics, particularly in the face of increasing antibiotic resistance.
Used in Research and Development:
ACP is used as a subject of study in the field of microbiology and pharmaceutical research. Its unique structure and mechanism of action provide valuable insights into the development of novel antibiotics and potential treatments for a variety of bacterial infections. Researchers are interested in exploring its potential applications and optimizing its properties for clinical use.
Used in Drug Resistance Studies:
1-(4-amino-3-carbamoyl-1H-pyrazol-5-yl)-1,4-anhydropentitol is used in the investigation of bacterial resistance to antibiotics. Understanding how ACP interacts with bacterial ribosomes and its effectiveness against resistant strains can contribute to the development of strategies to combat antibiotic resistance and improve the overall efficacy of antibiotic treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 62160-01-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,1,6 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 62160-01:
(7*6)+(6*2)+(5*1)+(4*6)+(3*0)+(2*0)+(1*1)=84
84 % 10 = 4
So 62160-01-4 is a valid CAS Registry Number.
62160-01-4Relevant academic research and scientific papers
C-Nucleoside Studies. Part 17. The Synthesis of 3(5)-Carbamoyl-5(3)-β-D-ribofuranosylpyrazole (4-Deoxypyrazofurin) and 4-Amino-3(5)-carbamoyl-5(3)-β-D-ribofuranosylpyrazole
Buchanan, J. Grant,Saxena, Naveen K.,Wightman, Richard H.
, p. 2367 - 2371 (2007/10/02)
4-Amino-3(5)-cyano-5(3)-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazole (10) was converted into the diazopyrazole (11) by treatment with nitrous acid.On photolysis in aqueous dioxane using visible light compound (11) gave 3(5)-cyano-5(3)-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazole (12) which formed the corresponding amide (13) (75percent) with alkaline hydrogen peroxide.Deprotection of compound (13) with methanolic ammonia afforded 3(5)-carbamoyl-5(3)-β-D-ribofuranosylpyrazole (4) (74percent), the 4-deoxy analogue of pyrazofurin (3). 3(5)-Cyano-4-nitro-5(3)-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazole (1) reacted with dihydropyran and toluene-p-sulphonic acid to give the N-tetrahydropyranyl) derivative (21) (66.5percent).Hydrolysis of the nitrile group of compound (21), using alkaline hydrogen peroxide, afforded the amide (22) (71percent) which was deprotected to give 3(5)-carbamoyl-4-nitro-5(3)-β-D-ribofuranosylpyrazole (23) (83percent).Catalytic reduction of compound (23) gave 4-amino-3(5)-carbamoyl-5(3)-β-D-ribofuranosylpyrazole (5) (83percent) which could be converted into formycin B (24) (69percent).
