62205-20-3Relevant academic research and scientific papers
Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors
Reyes-Ramírez, Adelfo,Leyte-Lugo, Martha,Figueroa, Mario,Serrano-Alba, Trinidad,González-Andrade, Martín,Mata, Rachel
experimental part, p. 2699 - 2708 (2011/07/08)
Several analogs of gigantol (1) were synthesized to evaluate their effect on the complexes Ca2+-calmodulin (CaM) and Ca2+-CaM-CaM sensitive phosphodiesterase 1 (PDE1). The compounds belong to four structural groups including, 1,2-dip
