6222-19-1Relevant academic research and scientific papers
Convenient Selective Monoacylation of 1,n-Diols Catalyzed by Ion-Exchange Resins
Nischiguchi, Takeshi,Fujisaki, Shizuo,Ishii, Yasuhiro,Yano, Yoshihiro,Nishida, Akiko
, p. 1191 - 1195 (2007/10/02)
Several 1,n-diols, ranging from 1,2-ethanediol to 1,16-hexadecanediol, were selectively monoacylated by transestrification in ester/octane solvent mixtures catalyzed by strongly acidic ion-exchange resisns.This method of selective esterification is quite simple and practical.The selectivity for monoester formation and initial rates of monoester formation depended on the ester/octane ratio of the solvents.The reasons for the selectivity are as follows: (1) The sulfonic acid-type ion-exchange resins usually contain 50-80percent water, and a strongly acidic aqueous layer is formed on the surface of the resins. (2) A partition equilibrium between the aqueous layer and the aprotic ester/octane layer is setup, and diols have higher partition coefficients than the product monoesters. (3) Acylation of the alcohols occurs in the aqueous layer and/or at the interface between the aqueous and the nonaqueous liquid layer. (4) The formed monoesters move away from the aqueous layer into the aprotic layer.
NEW OXIDATIVE ESTERIFICATION OF ALCOHOLS WITH ALDEHYDES BY THE Br2-HMPT-NaHCO3.
Al Neirabeyeh, Mamdouh,Pujol, M. Dolors
, p. 2273 - 2276 (2007/10/02)
A new aldehyde-mediated oxidative esterification using a bromine/HMPT complex in the presence of sodium hydrogen carbonate is described.
