62221-84-5Relevant academic research and scientific papers
METHOD FOR THE PRODUCTION OF MUSK FRAGRANCE INGREDIENT
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Page/Page column 66-67, (2022/02/05)
A method for making intermediate compounds suitable for making muscenone, the compositions made by said methods, the various uses of said compositions, and enzyme variants useful in said methods.
92. A Short Synthesis of (+/-)-Muscone
Rautenstrauch, Valentin,Snowden, Roger L.,Linder, Simon M.
, p. 896 - 901 (2007/10/02)
(+/-)-Muscone ((+/-)-1) has been synthesized in three steps from 2-(2'-methylprop-2'-enyl)cyclododecan-1-one (2).The synthesis involves two key transformations: a Lewis-acid-mediated intramolecular ene reaction (2 -> 3) and the β-cleavage of the bicyclic potassium alkoxide 3a' to the macrocyclic enone (Z)-11.
