62230-47-1

Downstream Products

• 38027-31-5 C₂₀H₂₄N₆ 
• 38027-28-0 C₁₉H₂₂N₆ 
• 39254-62-1 2--1.3.4-triaza-2.4-heptadien-6-in 
• 38027-25-7 C₂₄H₂₄N₆ 
• 102635-84-7 4-Methyl-N-(2-phenyl-4-thioxo-4H-quinazolin-3-yl)-benzamidine 
• 102635-87-0 4-Methyl-N-(4-thioxo-2-p-tolyl-4H-quinazolin-3-yl)-benzamidine 
• 87522-15-4 4-oxido-6,8-diphenyl-2-p-tolylpyrido<2,1-f><1,2,4>triazin-9-ium 
• 111425-19-5 Benzoic acid N'-(6-oxo-3-p-tolyl-1,6-dihydro-[1,2,4]triazin-5-yl)-N-phenyl-hydrazide 
• 111425-22-0 4-Methyl-benzoic acid N'-(6-oxo-3-p-tolyl-1,6-dihydro-[1,2,4]triazin-5-yl)-N-phenyl-hydrazide 
• 111425-24-2 4-Methoxy-benzoic acid N'-(6-oxo-3-p-tolyl-1,6-dihydro-[1,2,4]triazin-5-yl)-N-phenyl-hydrazide 
• 84438-18-6 N-[2-(5-p-Tolyl-[1,3,4]thiadiazol-2-yl)-phenyl]-benzamide 
• 91020-70-1 5-Phenyl-2-p-tolyl-[1,2,4]triazolo[1,5-c]quinazoline 
• 19081-74-4 N¹,N^1'-Bis-<4-methyl-benzimidoyl>-oxalamidrazon 
• 19375-73-6 N¹-<2-Hydroxy-1,3-dioxo-indanyl-(2)>-p-toluylsaeure-amidrazon 

Relevant academic research and scientific papers

Amidrazones and derivatives thereof

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging) which contain novel amidrazones and derivatives thereof. Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.