62234-29-1

Basic information

• Product Name: Butanoic acid, 4-amino-2-[[(4-methylphenyl)sulfonyl]amino]-, (S)-
• CAS NO: 62234-29-1
• Molecular Formula: C11H16N2O4S
• Molecular Weight: 272.325
• Mol File: 62234-29-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-amino-2-[[(4-methylphenyl)sulfonyl]amino]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-amino-2-[[(4-methylphenyl)sulfonyl]amino]-, (S)-(62234-29-1)
• EPA Substance Registry System: Butanoic acid, 4-amino-2-[[(4-methylphenyl)sulfonyl]amino]-, (S)-(62234-29-1)

Safety Data

• Hazardous Substances Data: 62234-29-1(Hazardous Substances Data)

Upstream product

• 116729-82-9 (S)-methyl 3-cyano-2-<(p-toluenesulfonyl)amino>propionate 
• 59642-37-4 N-(p-toluenesulfonyl)L-asparagine methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 42749-49-5 N²-<(4-methylphenyl)sulfonyl>-L-glutamine 
• 131102-73-3 N-((S)-2-oxo-pyrrolidin-3-yl)-toluene-4-sulfonamide 
• 115146-24-2 (S)-4-benzyloxycarbonylamino-2-(toluene-4-sulfonylamino)-butyric acid 
• 104097-65-6 N-(toluene-4-sulfonyl)-L-aspartic acid-4-nitrile 

Downstream Products

• 13558-07-1 N²-<(1,1-dimethylethoxy)carbonyl>-N⁴-<(4-methylphenyl)sulfonyl>-2,3-diaminobutanoic acid 
• 73143-97-2 (S)-2,4-diamino-butyric acid ; hydrobromide 
• 116107-04-1 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyric acid-[(S)-2-oxo-1-(toluene-4-sulfonyl)-pyrrolidin-3-ylamide] 
• 114961-90-9 N,N'-bis-[(S)-2-oxo-1-(toluene-4-sulfonyl)-pyrrolidin-3-yl]-urea 
• 73116-13-9 (3S)-cis-3,6-bis-[2-(toluene-4-sulfonylamino)-ethyl]-piperazine-2,5-dione 
• 103506-94-1 N-benzyloxycarbonyl-glycin-[(S)-2-oxo-1-(toluene-4-sulfonyl)-pyrrolidin-3-ylamide] 
• 108016-79-1 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl=>(S)-2-amino-4-(toluene-4-sulfonylamino)-butyryl=>L-leucine ethyl ester 
• 121057-55-4 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl=>-L_S-threonyl=>(S)-2-amino-4-(toluene-4-sulfonylamino)-butyryl=>L_S-threonine ethyl ester 
• 124136-49-8 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl=>(S)-2-amino-4-(toluene-4-sulfonylamino)-butyryl=>L_S-threonine ethyl ester 
• 120969-53-1 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl=>(S)-2-amino-4-(toluene-4-sulfonylamino)-butyryl=>L-serine methyl ester 
• 123104-01-8 N-benzyloxycarbonyl-glycyl=>(S)-2-amino-4-(toluene-4-sulfonylamino)-butyryl=>glycine ethyl ester 
• 117888-36-5 N-[(S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl]-L_S-threonine ethyl ester 
• 121599-55-1 N-[(S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyryl]-L_S-threonine 
• 108479-05-6 (S)-2-benzyloxycarbonylamino-4-(toluene-4-sulfonylamino)-butyric acid hydrazide 

Relevant articles and documents

(S)-2-methyl-1,4,5,6-tetrahydromethylpyrimidine-4-carboxylic acid synthesis method

The present invention relates to a (S)-2-methyl-1,4,5,6-tetrahydromethylpyrimidine-4-carboxylic acid synthesis method. According to the method, L-glutamine is used as a raw material, the alpha-amino of the L-glutamine is protected with a protection group, a decarbonylating agent is added, a Hofmann degradation reaction is performed to remove the carbonyl group attached to the remaining amino, the protection group is removed to obtain L-2,4-diaminobutyric acid, and finally the prepared L-2,4-diaminobutyric acid and trimethyl orthoacetate are subjected to a ring forming reaction to obtain the (S)-2-methyl-1,4,5,6-tetrahydromethylpyrimidine-4-carboxylic acid. Compared to the method in the prior art, the method of the present invention has the following characteristics that the chemical synthesis route is provided, the steps of the synthesis process are simple, the raw materials are easy to obtain, the product purity is high, and the method is suitable for large-scale industrial production.